An Epidemic of Urinary Retention Caused by Dimethylaminopropionitrile

James P. Keogh, Debra Wertheimer, Alan Pestronk, Rebecca Moreland

Research output: Contribution to journalArticle

Abstract

An epidemic of urinary retention among workers in a polyurethane manufacturing plant was discovered in the spring of 1978. The most severely affected workers had neurogenic bladders confirmed by cystometrograms and mild sensory peripheral neuropathy. A survey of the plant disclosed increased incidence of urinary retention, muscle weakness, paresthesia, insomnia, and sexual dysfunction in exposed workers. A catalyst containing dimethylaminopropionitrile was identified as the probable causative agent, and after its removal no new cases occurred.

Original languageEnglish (US)
Pages (from-to)746-749
Number of pages4
JournalJournal of the American Medical Association
Volume243
Issue number8
DOIs
StatePublished - Feb 22 1980

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Urinary Retention
Neurogenic Urinary Bladder
Polyurethanes
Paresthesia
Muscle Weakness
Sleep Initiation and Maintenance Disorders
Peripheral Nervous System Diseases
Incidence
dimethylaminopropionitrile
Manufacturing and Industrial Facilities
Surveys and Questionnaires

ASJC Scopus subject areas

  • Medicine(all)

Cite this

An Epidemic of Urinary Retention Caused by Dimethylaminopropionitrile. / Keogh, James P.; Wertheimer, Debra; Pestronk, Alan; Moreland, Rebecca.

In: Journal of the American Medical Association, Vol. 243, No. 8, 22.02.1980, p. 746-749.

Research output: Contribution to journalArticle

Keogh, James P. ; Wertheimer, Debra ; Pestronk, Alan ; Moreland, Rebecca. / An Epidemic of Urinary Retention Caused by Dimethylaminopropionitrile. In: Journal of the American Medical Association. 1980 ; Vol. 243, No. 8. pp. 746-749.
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