An Enzyme-Linked Immunosorbent Assay (ELISA) for Antibodies to Thyroglobulin

Alister Voller, Dennis E. Bidwell, C. Lynne Burek

Research output: Contribution to journalArticlepeer-review

Abstract

An enzyme-linked immunosorbent assay (ELISA) was developed for the detection of thyroglobulin antibodies. The ELISA was compared with an indirect hemagglutination technique using thyroglobulin coupled to human group O erythrocytes with chromic chloride. The overall correlation between the two techniques was 0.82 (P < 0.001). ELISA proved to be suitable for large-scale screening, as all reagents are stable, with a long shelf life. However, because of its lower sensitivity, it will probably not as yet replace the chromic chloride IHA test.

Original languageEnglish (US)
Pages (from-to)402-405
Number of pages4
JournalProceedings of the Society for Experimental Biology and Medicine
Volume163
Issue number3
DOIs
StatePublished - Mar 1980

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Fingerprint Dive into the research topics of 'An Enzyme-Linked Immunosorbent Assay (ELISA) for Antibodies to Thyroglobulin'. Together they form a unique fingerprint.

Cite this