An atypical case of dermatomyositis associated with chromophobe renal cell carcinoma

Michael David George; Arash H. Lahouti; Lisa Christopher-Stine

doi:10.1136/bcr-2015-212387

An atypical case of dermatomyositis associated with chromophobe renal cell carcinoma

Michael David George, Arash H. Lahouti, Lisa Christopher-Stine

School of Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

Dermatomyositis and polymyositis are the major idiopathic inflammatory myopathies in adults. They are associated with an elevated risk of malignancy. However, renal tumours have rarely been described in dermatomyositis patients. We report the case of a 27-year-old Caucasian man with chromophobe renal cell cancer (ChRCC) and antinuclear matrix protein (NXP-2)-associated dermatomyositis. To the best of our knowledge, there are no previous reports of ChRCC presenting with dermatomyositis.

Original language	English (US)
Article number	212387
Journal	BMJ case reports
Volume	2016
DOIs	https://doi.org/10.1136/bcr-2015-212387
State	Published - Jan 19 2016

ASJC Scopus subject areas

Medicine(all)

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abstract = "Dermatomyositis and polymyositis are the major idiopathic inflammatory myopathies in adults. They are associated with an elevated risk of malignancy. However, renal tumours have rarely been described in dermatomyositis patients. We report the case of a 27-year-old Caucasian man with chromophobe renal cell cancer (ChRCC) and antinuclear matrix protein (NXP-2)-associated dermatomyositis. To the best of our knowledge, there are no previous reports of ChRCC presenting with dermatomyositis.",

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AB - Dermatomyositis and polymyositis are the major idiopathic inflammatory myopathies in adults. They are associated with an elevated risk of malignancy. However, renal tumours have rarely been described in dermatomyositis patients. We report the case of a 27-year-old Caucasian man with chromophobe renal cell cancer (ChRCC) and antinuclear matrix protein (NXP-2)-associated dermatomyositis. To the best of our knowledge, there are no previous reports of ChRCC presenting with dermatomyositis.

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