An Arresting Story about Basement Membrane Invasion

Research output: Contribution to journalShort survey

Abstract

In this issue of Developmental Cell, Matus et al. (2015) reveal that to invade past basement membrane, the C. elegans anchor cell must cease dividing before differentiating and expressing pro-invasion genes. This demonstration of invasion and proliferation as mutually incompatible cell states has implications for our understanding of cancer metastasis. In this issue of Developmental Cell, Matus et al. (2015) reveal that to invade past basement membrane, the C. elegans anchor cell must cease dividing before differentiating and expressing pro-invasion genes. This demonstration of invasion and proliferation as mutually incompatible cell states has implications for our understanding of cancer metastasis.

Original languageEnglish (US)
Pages (from-to)143-144
Number of pages2
JournalDevelopmental Cell
Volume35
Issue number2
DOIs
StatePublished - Oct 26 2015

ASJC Scopus subject areas

  • Molecular Biology
  • Biochemistry, Genetics and Molecular Biology(all)
  • Developmental Biology
  • Cell Biology

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