An area essential for linking word meanings to word forms: Evidence from primary progressive aphasia

D. S. Race; K. Tsapkini; J. Crinion; M. Newhart; C. Davis; Y. Gomez; A. E. Hillis; A. V. Faria

doi:10.1016/j.bandl.2013.09.004

An area essential for linking word meanings to word forms: Evidence from primary progressive aphasia

D. S. Race, K. Tsapkini, J. Crinion, M. Newhart, C. Davis, Y. Gomez, A. E. Hillis, A. V. Faria

School of Medicine

Research output: Contribution to journal › Article

Abstract

We investigated the relationship between deficits in naming and areas of focal atrophy in primary progressive aphasia (a neurodegenerative disease that specifically affects language processing). We tested patients, across multiple input modalities, on traditional naming tasks (picture naming) and more complex tasks (sentence completion with a name, naming in response to a question) and obtained high resolution MRI. Across most tasks, error rates were correlated with atrophy in the left middle and posterior inferior temporal gyrus. Overall, this result converges with prior literature suggesting that this region plays a major role in modality independent lexical processing.

Original language	English (US)
Pages (from-to)	167-176
Number of pages	10
Journal	Brain and Language
Volume	127
Issue number	2
DOIs	https://doi.org/10.1016/j.bandl.2013.09.004
State	Published - Nov 1 2013

Keywords

Inferior temporal cortex
Lexical access
MRI
Naming
Neurodegeneration
Primary progressive aphasia

ASJC Scopus subject areas

Language and Linguistics
Experimental and Cognitive Psychology
Linguistics and Language
Cognitive Neuroscience
Speech and Hearing

Access to Document

10.1016/j.bandl.2013.09.004

Fingerprint Dive into the research topics of 'An area essential for linking word meanings to word forms: Evidence from primary progressive aphasia'. Together they form a unique fingerprint.

Cite this

Race, D. S., Tsapkini, K., Crinion, J., Newhart, M., Davis, C., Gomez, Y., Hillis, A. E., & Faria, A. V. (2013). An area essential for linking word meanings to word forms: Evidence from primary progressive aphasia. Brain and Language, 127(2), 167-176. https://doi.org/10.1016/j.bandl.2013.09.004

@article{c9dafc44e16c4aa89e81625a4215b4e2,

title = "An area essential for linking word meanings to word forms: Evidence from primary progressive aphasia",

abstract = "We investigated the relationship between deficits in naming and areas of focal atrophy in primary progressive aphasia (a neurodegenerative disease that specifically affects language processing). We tested patients, across multiple input modalities, on traditional naming tasks (picture naming) and more complex tasks (sentence completion with a name, naming in response to a question) and obtained high resolution MRI. Across most tasks, error rates were correlated with atrophy in the left middle and posterior inferior temporal gyrus. Overall, this result converges with prior literature suggesting that this region plays a major role in modality independent lexical processing.",

keywords = "Inferior temporal cortex, Lexical access, MRI, Naming, Neurodegeneration, Primary progressive aphasia",

author = "Race, {D. S.} and K. Tsapkini and J. Crinion and M. Newhart and C. Davis and Y. Gomez and Hillis, {A. E.} and Faria, {A. V.}",

year = "2013",

month = nov,

day = "1",

doi = "10.1016/j.bandl.2013.09.004",

language = "English (US)",

volume = "127",

pages = "167--176",

journal = "Brain and Language",

issn = "0093-934X",

publisher = "Academic Press Inc.",

number = "2",

}

TY - JOUR

T1 - An area essential for linking word meanings to word forms

T2 - Evidence from primary progressive aphasia

AU - Race, D. S.

AU - Tsapkini, K.

AU - Crinion, J.

AU - Newhart, M.

AU - Davis, C.

AU - Gomez, Y.

AU - Hillis, A. E.

AU - Faria, A. V.

PY - 2013/11/1

Y1 - 2013/11/1

N2 - We investigated the relationship between deficits in naming and areas of focal atrophy in primary progressive aphasia (a neurodegenerative disease that specifically affects language processing). We tested patients, across multiple input modalities, on traditional naming tasks (picture naming) and more complex tasks (sentence completion with a name, naming in response to a question) and obtained high resolution MRI. Across most tasks, error rates were correlated with atrophy in the left middle and posterior inferior temporal gyrus. Overall, this result converges with prior literature suggesting that this region plays a major role in modality independent lexical processing.

AB - We investigated the relationship between deficits in naming and areas of focal atrophy in primary progressive aphasia (a neurodegenerative disease that specifically affects language processing). We tested patients, across multiple input modalities, on traditional naming tasks (picture naming) and more complex tasks (sentence completion with a name, naming in response to a question) and obtained high resolution MRI. Across most tasks, error rates were correlated with atrophy in the left middle and posterior inferior temporal gyrus. Overall, this result converges with prior literature suggesting that this region plays a major role in modality independent lexical processing.

KW - Inferior temporal cortex

KW - Lexical access

KW - MRI

KW - Naming

KW - Neurodegeneration

KW - Primary progressive aphasia

UR - http://www.scopus.com/inward/record.url?scp=84888074363&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84888074363&partnerID=8YFLogxK

U2 - 10.1016/j.bandl.2013.09.004

DO - 10.1016/j.bandl.2013.09.004

M3 - Article

C2 - 24183469

AN - SCOPUS:84888074363

VL - 127

SP - 167

EP - 176

JO - Brain and Language

JF - Brain and Language

SN - 0093-934X

IS - 2

ER -