Abstract
We investigated the relationship between deficits in naming and areas of focal atrophy in primary progressive aphasia (a neurodegenerative disease that specifically affects language processing). We tested patients, across multiple input modalities, on traditional naming tasks (picture naming) and more complex tasks (sentence completion with a name, naming in response to a question) and obtained high resolution MRI. Across most tasks, error rates were correlated with atrophy in the left middle and posterior inferior temporal gyrus. Overall, this result converges with prior literature suggesting that this region plays a major role in modality independent lexical processing.
Original language | English (US) |
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Pages (from-to) | 167-176 |
Number of pages | 10 |
Journal | Brain and Language |
Volume | 127 |
Issue number | 2 |
DOIs | |
State | Published - Nov 2013 |
Keywords
- Inferior temporal cortex
- Lexical access
- MRI
- Naming
- Neurodegeneration
- Primary progressive aphasia
ASJC Scopus subject areas
- Language and Linguistics
- Experimental and Cognitive Psychology
- Linguistics and Language
- Cognitive Neuroscience
- Speech and Hearing