The use of the bicyclo[3.3.1]nonane derived keto urethane (3) in a general synthesis of open chain and modified heterocyclic analogues of huperzine A was investigated and resulted in the preparation of the dimethylcarbamoyloxy analogue (27). Thiazole annulation by the Gewald procedure gave only the undesired regioisomer (36).
|Original language||English (US)|
|Number of pages||16|
|State||Published - Dec 31 1994|
ASJC Scopus subject areas
- Analytical Chemistry
- Organic Chemistry