An analysis of inflation times during balloon-assisted aneurysm coil embolization and ischemic complications

Alejandro M. Spiotta, Tarun Bhalla, Muhammad S. Hussain, Thinesh Sivapatham, Ayush Batra, Ferdinand Hui, Peter A. Rasmussen, Shaye I. Moskowitz

Research output: Contribution to journalArticlepeer-review

35 Scopus citations


Background and Purpose- The introduction of balloon remodeling has revolutionized the approach to coiling of wide-neck aneurysms. We studied the effects of balloon inflation during coil embolization on ischemic complications. Methods- A retrospective review was undertaken of the most recent 147 patients undergoing balloon remodeling for unruptured intracranial aneurysm coil embolization at a single institution (81 balloon, 66 unassisted). All underwent postprocedural MRI. Results- Among patients in the "balloon" group, the mean total inflation time was 18 minutes (range, 1-43), a mean number of inflations of 4 (range, 1-9), a mean maximum single inflation time of 7 minutes (range, 1-19), a mean reperfusion time of 2.2 minutes between inflations, and an average procedure time of 2 hours and 10 minutes. Asymptomatic diffusion-weighted imaging abnormalities were detected on postprocedural MRI in 21.5% of patients and symptomatic lesions were identified in 3.8%. Both silent and symptomatic ischemic rates were similar in the internal control group. Patients with ischemic findings were older and more likely have diabetes; no differences were found with respect to total balloon inflation time, number of inflations, maximum inflation time, or reperfusion times. Conclusions- We found no significant relationship between balloon inflation practices and ischemic events. Older and diabetic patients were more likely to have ischemic events develop.

Original languageEnglish (US)
Pages (from-to)1051-1055
Number of pages5
Issue number4
StatePublished - Apr 2011
Externally publishedYes


  • aneurysm
  • balloon
  • coil embolization
  • diffusion-weighted imaging
  • ischemia

ASJC Scopus subject areas

  • Clinical Neurology
  • Cardiology and Cardiovascular Medicine
  • Advanced and Specialized Nursing


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