TY - GEN
T1 - An agent-based simulation of a Tuberculosis epidemic
T2 - 2013 43rd Winter Simulation Conference - Simulation: Making Decisions in a Complex World, WSC 2013
AU - Kasaie, Parastu
AU - Dowdy, David W.
AU - David Kelton, W.
PY - 2013
Y1 - 2013
N2 - Tuberculosis (TB) transmission is a key factor for disease-control policy, but the timing and distribution of transmission and the role of social contacts remain obscure. We develop an agent-based simulation of a TB epidemic in a single population, and consider a hierarchically structured contact network in three levels, typical of airborne diseases. The parameters are adopted from the literature, and the model is calibrated to a setting of high TB incidence. We model the dynamics of transmission at the individual level, and study the timing of secondary infections from a single source throughout the duration of the disease. We compare the patterns of transmission among different networks and discuss implications. Sensitivity analysis of outputs indicates the robustness of the results to variations in the parameter values.
AB - Tuberculosis (TB) transmission is a key factor for disease-control policy, but the timing and distribution of transmission and the role of social contacts remain obscure. We develop an agent-based simulation of a TB epidemic in a single population, and consider a hierarchically structured contact network in three levels, typical of airborne diseases. The parameters are adopted from the literature, and the model is calibrated to a setting of high TB incidence. We model the dynamics of transmission at the individual level, and study the timing of secondary infections from a single source throughout the duration of the disease. We compare the patterns of transmission among different networks and discuss implications. Sensitivity analysis of outputs indicates the robustness of the results to variations in the parameter values.
UR - http://www.scopus.com/inward/record.url?scp=84894200412&partnerID=8YFLogxK
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U2 - 10.1109/WSC.2013.6721599
DO - 10.1109/WSC.2013.6721599
M3 - Conference contribution
AN - SCOPUS:84894200412
SN - 9781479939503
T3 - Proceedings of the 2013 Winter Simulation Conference - Simulation: Making Decisions in a Complex World, WSC 2013
SP - 2227
EP - 2238
BT - Proceedings of the 2013 Winter Simulation Conference - Simulation
Y2 - 8 December 2013 through 11 December 2013
ER -