Amyloidosis: Review and CT manifestations

Christos S Georgiades, Edward G. Neyman, Matthew A. Barish, Elliot K Fishman

Research output: Contribution to journalArticle

Abstract

Amyloidosis is a collection of disease entities that produce considerable morbidity and mortality and are increasing in prevalence. The imaging findings are problematically nonspecific and diverse. This lack of specificity is compounded by the fact that amyloidosis is strongly associated with and frequently coexists with many other chronic disease states that have their own imaging findings. Amyloidosis can involve any organ singly or in conjunction with other organs and can do so in the form of a focal, tumorlike lesion or an infiltrative process. In the proper clinical setting, that is, in a patient with chronic inflammatory disease and especially in a patient with multiple myeloma, amyloidosis should be considered as a possible cause of worsening or new symptoms or imaging findings. Occasionally, the radiologic findings may precede the clinical findings, thus providing the radiologist with the opportunity to contribute to the patient's care. However, to make a difference in patient care, the radiologist must be familiar with the diverse imaging findings of amyloidosis as well as the patient's clinical history, which could raise the suspicion of amyloidosis.

Original languageEnglish (US)
Pages (from-to)405-416
Number of pages12
JournalRadiographics : a review publication of the Radiological Society of North America, Inc
Volume24
Issue number2
StatePublished - Mar 2004

Fingerprint

Amyloidosis
Patient Care
Chronic Disease
Multiple Myeloma
Morbidity
Mortality

Keywords

  • Amyloidosis, **.68
  • Myeloma, **.34
  • Proteins, **.68

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Amyloidosis : Review and CT manifestations. / Georgiades, Christos S; Neyman, Edward G.; Barish, Matthew A.; Fishman, Elliot K.

In: Radiographics : a review publication of the Radiological Society of North America, Inc, Vol. 24, No. 2, 03.2004, p. 405-416.

Research output: Contribution to journalArticle

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