Ampa/kainate receptors

Nicole L. Stricker; Richard L. Huganir

doi:10.1093/acprof:oso/9780192632241.003.0006

Ampa/kainate receptors

Nicole L. Stricker, Richard L. Huganir

School of Medicine

Research output: Chapter in Book/Report/Conference proceeding › Chapter

1 Scopus citations

Abstract

The three major types of ionotropic glutamate receptors are the N-methyl-d-aspartate (NMDAR), a-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPAR), and kainate (KAR) receptors. AM PARs and KARs mediate fast excitatory transmission, whereas NMDARs mediate a slower component of synaptic transmission which is important for modulation of synaptic and neuronal function. This chapter focuses on the mechanisms of AMPA and kainate glutamate receptor assembly, synaptic localization, and surface expression.

Original language	English (US)
Title of host publication	Receptor and Ion-Channel Trafficking
Subtitle of host publication	Cell Biology of Ligand-Gated and Voltage-Sensitive Ion Channels
Publisher	Oxford University Press
ISBN (Electronic)	9780191724763
ISBN (Print)	9780192632241
DOIs	https://doi.org/10.1093/acprof:oso/9780192632241.003.0006
State	Published - Mar 22 2012

Keywords

AMPAR
Ionotropic glutamate receptors
Kainate glutamate receptors
NMDAR
Neuronal function
Surface expression
Synaptic localization

ASJC Scopus subject areas

General Neuroscience
General Medicine

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10.1093/acprof:oso/9780192632241.003.0006

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title = "Ampa/kainate receptors",

abstract = "The three major types of ionotropic glutamate receptors are the N-methyl-d-aspartate (NMDAR), a-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPAR), and kainate (KAR) receptors. AM PARs and KARs mediate fast excitatory transmission, whereas NMDARs mediate a slower component of synaptic transmission which is important for modulation of synaptic and neuronal function. This chapter focuses on the mechanisms of AMPA and kainate glutamate receptor assembly, synaptic localization, and surface expression.",

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AU - Stricker, Nicole L.

AU - Huganir, Richard L.

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N2 - The three major types of ionotropic glutamate receptors are the N-methyl-d-aspartate (NMDAR), a-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPAR), and kainate (KAR) receptors. AM PARs and KARs mediate fast excitatory transmission, whereas NMDARs mediate a slower component of synaptic transmission which is important for modulation of synaptic and neuronal function. This chapter focuses on the mechanisms of AMPA and kainate glutamate receptor assembly, synaptic localization, and surface expression.

AB - The three major types of ionotropic glutamate receptors are the N-methyl-d-aspartate (NMDAR), a-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPAR), and kainate (KAR) receptors. AM PARs and KARs mediate fast excitatory transmission, whereas NMDARs mediate a slower component of synaptic transmission which is important for modulation of synaptic and neuronal function. This chapter focuses on the mechanisms of AMPA and kainate glutamate receptor assembly, synaptic localization, and surface expression.

KW - AMPAR

KW - Ionotropic glutamate receptors

KW - Kainate glutamate receptors

KW - NMDAR

KW - Neuronal function

KW - Surface expression

KW - Synaptic localization

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DO - 10.1093/acprof:oso/9780192632241.003.0006

M3 - Chapter

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SN - 9780192632241

BT - Receptor and Ion-Channel Trafficking

PB - Oxford University Press

ER -

Ampa/kainate receptors

Abstract

Keywords

ASJC Scopus subject areas

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