Amniotic membrane transplantation for intraoperative conjunctival repair during trabeculectomy with mitomycin C

Gisèle Li, Thomas O'Hearn, Samuel Chi-Hung Yiu, Brian A. Francis

Research output: Contribution to journalArticle

Abstract

PURPOSE: To describe the use of amniotic membrane (AM) transplantation for the repair of conjunctival buttonholes during trabeculectomy with mitomycin C. METHODS: Four eyes of 3 patients with thin conjunctiva, precluding watertight conjunctival closure at the incision site with suturing, underwent intraoperative AM grafts over the leaking areas. RESULTS: In all eyes, a functional, nonleaking bleb was achieved. At the latest follow-up (8 to 30 mo), all eyes had intraocular pressures of 12 mm Hg or less without medications. CONCLUSIONS: AM transplantation was effective in the intraoperative closure of conjunctival buttonholes which developed at the incision line in 4 eyes. This intervention may be a useful addition to the glaucoma surgeon's repertoire of surgical techniques.

Original languageEnglish (US)
Pages (from-to)521-526
Number of pages6
JournalJournal of Glaucoma
Volume16
Issue number6
DOIs
StatePublished - Sep 2007
Externally publishedYes

Fingerprint

Trabeculectomy
Amnion
Mitomycin
Transplantation
Conjunctiva
Blister
Intraocular Pressure
Glaucoma
Transplants

Keywords

  • Amniotic membrane
  • Bleb leak
  • Conjunctival buttonhole
  • Glaucoma

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Amniotic membrane transplantation for intraoperative conjunctival repair during trabeculectomy with mitomycin C. / Li, Gisèle; O'Hearn, Thomas; Yiu, Samuel Chi-Hung; Francis, Brian A.

In: Journal of Glaucoma, Vol. 16, No. 6, 09.2007, p. 521-526.

Research output: Contribution to journalArticle

@article{3814fd54ab78472fafb2b29144f4da31,
title = "Amniotic membrane transplantation for intraoperative conjunctival repair during trabeculectomy with mitomycin C",
abstract = "PURPOSE: To describe the use of amniotic membrane (AM) transplantation for the repair of conjunctival buttonholes during trabeculectomy with mitomycin C. METHODS: Four eyes of 3 patients with thin conjunctiva, precluding watertight conjunctival closure at the incision site with suturing, underwent intraoperative AM grafts over the leaking areas. RESULTS: In all eyes, a functional, nonleaking bleb was achieved. At the latest follow-up (8 to 30 mo), all eyes had intraocular pressures of 12 mm Hg or less without medications. CONCLUSIONS: AM transplantation was effective in the intraoperative closure of conjunctival buttonholes which developed at the incision line in 4 eyes. This intervention may be a useful addition to the glaucoma surgeon's repertoire of surgical techniques.",
keywords = "Amniotic membrane, Bleb leak, Conjunctival buttonhole, Glaucoma",
author = "Gis{\`e}le Li and Thomas O'Hearn and Yiu, {Samuel Chi-Hung} and Francis, {Brian A.}",
year = "2007",
month = "9",
doi = "10.1097/IJG.0b013e3180408ddb",
language = "English (US)",
volume = "16",
pages = "521--526",
journal = "Journal of Glaucoma",
issn = "1057-0829",
publisher = "Lippincott Williams and Wilkins",
number = "6",

}

TY - JOUR

T1 - Amniotic membrane transplantation for intraoperative conjunctival repair during trabeculectomy with mitomycin C

AU - Li, Gisèle

AU - O'Hearn, Thomas

AU - Yiu, Samuel Chi-Hung

AU - Francis, Brian A.

PY - 2007/9

Y1 - 2007/9

N2 - PURPOSE: To describe the use of amniotic membrane (AM) transplantation for the repair of conjunctival buttonholes during trabeculectomy with mitomycin C. METHODS: Four eyes of 3 patients with thin conjunctiva, precluding watertight conjunctival closure at the incision site with suturing, underwent intraoperative AM grafts over the leaking areas. RESULTS: In all eyes, a functional, nonleaking bleb was achieved. At the latest follow-up (8 to 30 mo), all eyes had intraocular pressures of 12 mm Hg or less without medications. CONCLUSIONS: AM transplantation was effective in the intraoperative closure of conjunctival buttonholes which developed at the incision line in 4 eyes. This intervention may be a useful addition to the glaucoma surgeon's repertoire of surgical techniques.

AB - PURPOSE: To describe the use of amniotic membrane (AM) transplantation for the repair of conjunctival buttonholes during trabeculectomy with mitomycin C. METHODS: Four eyes of 3 patients with thin conjunctiva, precluding watertight conjunctival closure at the incision site with suturing, underwent intraoperative AM grafts over the leaking areas. RESULTS: In all eyes, a functional, nonleaking bleb was achieved. At the latest follow-up (8 to 30 mo), all eyes had intraocular pressures of 12 mm Hg or less without medications. CONCLUSIONS: AM transplantation was effective in the intraoperative closure of conjunctival buttonholes which developed at the incision line in 4 eyes. This intervention may be a useful addition to the glaucoma surgeon's repertoire of surgical techniques.

KW - Amniotic membrane

KW - Bleb leak

KW - Conjunctival buttonhole

KW - Glaucoma

UR - http://www.scopus.com/inward/record.url?scp=34548677950&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=34548677950&partnerID=8YFLogxK

U2 - 10.1097/IJG.0b013e3180408ddb

DO - 10.1097/IJG.0b013e3180408ddb

M3 - Article

C2 - 17873712

AN - SCOPUS:34548677950

VL - 16

SP - 521

EP - 526

JO - Journal of Glaucoma

JF - Journal of Glaucoma

SN - 1057-0829

IS - 6

ER -