Aminocaproic Acid Decreases Secondary Hemorrhage After Traumatic Hyphema

John J. Mcgetrick, Lee M. Jampol, Morton F. Goldberg, Marcel Frenkel, Richard G. Fiscella

Research output: Contribution to journalArticle


Forty-eight patients (49 eyes) had nonperforating traumatic hyphema. Twenty-eight patients (28 eyes with hyphema) received oral aminocaproic acid, an antifibrinolytic agent, in a dosage of 100 mg/kg every four hours for five days, up to a maximum daily dose of 30 g. Twenty patients (21 eyes with hyphema) received placebo in an identical regimen. One eye treated with aminocaproic acid rebled; seven eyes receiving the placebo rebled. The results of this study show a statistically significant reduction in the incidence of secondary hemorrhage in the patients receiving aminocaproic acid.

Original languageEnglish (US)
Pages (from-to)1031-1033
Number of pages3
JournalArchives of ophthalmology
Issue number7
StatePublished - Jul 1983
Externally publishedYes


ASJC Scopus subject areas

  • Ophthalmology

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