American Brachytherapy Society consensus guidelines for interstitial brachytherapy for vaginal cancer

Sushil Beriwal, D. Jeffrey Demanes, Beth Erickson, Ellen Jones, Jennifer F. De Los Santos, Robert A. Cormack, Catheryn Yashar, Jason J. Rownd, Akila N. Viswanathan

Research output: Contribution to journalArticlepeer-review

100 Scopus citations

Abstract

Purpose: To present recommendations for the use of interstitial brachytherapy in patients with vaginal cancer or recurrent endometrial cancer in the vagina. Methods: A panel of members of the American Brachytherapy Society reviewed the literature, supplemented that with their clinical experience, and formulated recommendations for interstitial brachytherapy for primary or recurrent cancers in the vagina. Results: Patients with bulky disease (approximately >0.5. cm thick) should be considered for treatment with interstitial brachytherapy. The American Brachytherapy Society reports specific recommendations for techniques, target volume definition, and dose-fractionation schemes. Three-dimensional treatment planning is recommended with CT scan and/or MRI. The treatment plan should be optimized to conform to the clinical target volume and should reduce the dose to critical organs, including the rectum, bladder, urethra, and sigmoid colon. Suggested doses in combination with external beam radiation therapy and summated equivalent doses in 2. Gy fractions are tabulated. Conclusion: Recommendations are made for interstitial brachytherapy for vaginal cancer and recurrent disease in the vagina. Practitioners and cooperative groups are encouraged to use these recommendations to formulate treatment and dose-reporting policies. Such a process will result in meaningful outcome comparisons, promote technical advances, and lead to appropriate utilization of these techniques.

Original languageEnglish (US)
Pages (from-to)68-75
Number of pages8
JournalBrachytherapy
Volume11
Issue number1
DOIs
StatePublished - Jan 2012
Externally publishedYes

Keywords

  • HDR
  • Interstitial
  • Vagina

ASJC Scopus subject areas

  • Oncology
  • Radiology Nuclear Medicine and imaging

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