Abstract
"The etiology of Alzheimer's Disease, the most common form of dementia in late-life, is unknown. There are no therapies that effectively ameliorate the symptoms, nor stop the eventual deterioration of cognition, function, and behavior. Research over the past several decades has identified a number of modifiable factors that increase the risk for Alzheimer's Disease, as well as those associated with a reduction in risk. This chapter reviews the current research literature on risk factors for Alzheimer's Disease and reviews potential strategies for its prevention."
| Original language | English (US) |
|---|---|
| Title of host publication | Principles and Practice of Geriatric Psychiatry |
| Subtitle of host publication | Third Edition |
| Publisher | John Wiley and Sons |
| Pages | 271-280 |
| Number of pages | 10 |
| ISBN (Print) | 9780470747230 |
| DOIs | |
| State | Published - Dec 2 2010 |
| Externally published | Yes |
Keywords
- 'glucocorticoid cascade' - invoked to underlie hippocampal damage, cognitive impairment observed with chronic stress in aged organisms
- Advanced glycation end-products (AGE)
- Alzheimer's disease - risk factors and preventive strategies
- Dementia, cause of disability and mortality among the elderly
- Early-onset forms of AD - no single identified cause of disorder
- Mechanisms, underlying sex-specific difference - in AD risk, presently unknown
- Risk factors for cardiovascular disease - and AD
- Scientific literature, identifying - risk factors putatively associated with AD
- Strategies for prevention of AD
- Traumatic Brain Injury (TBI), risk of AD - persons with history of head trauma
ASJC Scopus subject areas
- General Medicine