Alzheimer's Disease: Risk Factors and Preventive Strategies

Joann T. Tschanz, John C.S. Breitner

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

"The etiology of Alzheimer's Disease, the most common form of dementia in late-life, is unknown. There are no therapies that effectively ameliorate the symptoms, nor stop the eventual deterioration of cognition, function, and behavior. Research over the past several decades has identified a number of modifiable factors that increase the risk for Alzheimer's Disease, as well as those associated with a reduction in risk. This chapter reviews the current research literature on risk factors for Alzheimer's Disease and reviews potential strategies for its prevention."

Original languageEnglish (US)
Title of host publicationPrinciples and Practice of Geriatric Psychiatry
Subtitle of host publicationThird Edition
PublisherJohn Wiley and Sons
Pages271-280
Number of pages10
ISBN (Print)9780470747230
DOIs
StatePublished - Dec 2 2010
Externally publishedYes

Keywords

  • 'glucocorticoid cascade' - invoked to underlie hippocampal damage, cognitive impairment observed with chronic stress in aged organisms
  • Advanced glycation end-products (AGE)
  • Alzheimer's disease - risk factors and preventive strategies
  • Dementia, cause of disability and mortality among the elderly
  • Early-onset forms of AD - no single identified cause of disorder
  • Mechanisms, underlying sex-specific difference - in AD risk, presently unknown
  • Risk factors for cardiovascular disease - and AD
  • Scientific literature, identifying - risk factors putatively associated with AD
  • Strategies for prevention of AD
  • Traumatic Brain Injury (TBI), risk of AD - persons with history of head trauma

ASJC Scopus subject areas

  • Medicine(all)

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