Alzheimer’s disease

A. Soldan; Y. Gazes; Y. Stern

doi:10.1016/B978-0-12-809324-5.06319-7

Alzheimer’s disease

A. Soldan, Y. Gazes, Y. Stern

School of Medicine

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

This article provides a comprehensive review of Alzheimer’s disease, providing a description of the history, symptoms, causes, diagnosis, genetics, risk factors, treatment, and societal impact of the disease. Alzheimer’s disease (AD) is characterized behaviorally by progressive memory and cognitive decline and physiologically by the presence of amyloid beta plaques and neurofibrillary tangles in the brain. The underlying cause of AD as well as its treatment is still under investigation. A number of valuable diagnostic tools have been developed and continue to be improved. Risk factors for AD include age, genetic predisposition, environmental factors, cardiovascular diseases, diabetes, and diet.

Original language	English (US)
Title of host publication	The Curated Reference Collection in Neuroscience and Biobehavioral Psychology
Publisher	Elsevier Science Ltd.
Pages	108-115
Number of pages	8
ISBN (Electronic)	9780128093245
DOIs	https://doi.org/10.1016/B978-0-12-809324-5.06319-7
State	Published - Jan 1 2016

Keywords

Amyloid beta plaques
Amyloid cascade hypothesis
Biomarkers
Cholinergic hypothesis
Cognitive reserve
Genetics
Risk factors
Social impact
Tau protein tangles
Treatment

ASJC Scopus subject areas

General Medicine

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10.1016/B978-0-12-809324-5.06319-7

Cite this

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KW - Biomarkers

KW - Cholinergic hypothesis

KW - Cognitive reserve

KW - Genetics

KW - Risk factors

KW - Social impact

KW - Tau protein tangles

KW - Treatment

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Alzheimer’s disease

Abstract

Keywords

ASJC Scopus subject areas

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