Alzheimer’s disease

A. Soldan, Y. Gazes, Y. Stern

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

This article provides a comprehensive review of Alzheimer’s disease, providing a description of the history, symptoms, causes, diagnosis, genetics, risk factors, treatment, and societal impact of the disease. Alzheimer’s disease (AD) is characterized behaviorally by progressive memory and cognitive decline and physiologically by the presence of amyloid beta plaques and neurofibrillary tangles in the brain. The underlying cause of AD as well as its treatment is still under investigation. A number of valuable diagnostic tools have been developed and continue to be improved. Risk factors for AD include age, genetic predisposition, environmental factors, cardiovascular diseases, diabetes, and diet.

Original languageEnglish (US)
Title of host publicationThe Curated Reference Collection in Neuroscience and Biobehavioral Psychology
PublisherElsevier Science Ltd.
Pages108-115
Number of pages8
ISBN (Electronic)9780128093245
DOIs
StatePublished - Jan 1 2016

Keywords

  • Amyloid beta plaques
  • Amyloid cascade hypothesis
  • Biomarkers
  • Cholinergic hypothesis
  • Cognitive reserve
  • Genetics
  • Risk factors
  • Social impact
  • Tau protein tangles
  • Treatment

ASJC Scopus subject areas

  • Medicine(all)

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