Alterations of systolic left ventricular twist after acute myocardial infarction

Jérôme Garot, Olivier Pascal, Benoît Diébold, Geneviève Derumeaux, Bernhard L. Gerber, Jean Luc Dubois-Randé, Joao Lima, Pascal Guéret

Research output: Contribution to journalArticle

Abstract

We sought to characterize the alterations of left ventricular (LV) twist after acute myocardial infarction in humans and to study their relationship to usual parameters of LV function. Systolic LV twist was measured by color tissue Doppler echocardiography (TDE) in 34 patients after anterior myocardial infarction and in 20 controls. In a subset of controls and patients, the assessment of LV twist by TDE was validated against magnetic resonance (MR) tissue tagging with good agreement between the two methods. Myocardial ischemia was responsible for a decrease in LV twist in infarct patients (P <0.01). The decrease in LV twist was correlated with the extent of the asynergic area and global LV function as assessed by LV cineangiography (P <0.001). Thus acute myocardial ischemia is responsible for a decrease in LV twist that is related to global LV function. Color TDE is a promising technique for straightforward assessment of LV twist in humans.

Original languageEnglish (US)
JournalAmerican Journal of Physiology - Heart and Circulatory Physiology
Volume282
Issue number1 51-1
Publication statusPublished - 2002

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Keywords

  • Doppler
  • Echocardiography

ASJC Scopus subject areas

  • Physiology

Cite this

Garot, J., Pascal, O., Diébold, B., Derumeaux, G., Gerber, B. L., Dubois-Randé, J. L., ... Guéret, P. (2002). Alterations of systolic left ventricular twist after acute myocardial infarction. American Journal of Physiology - Heart and Circulatory Physiology, 282(1 51-1).