Alterations in DNA methylation in human colon neoplasia

Research output: Contribution to journalArticlepeer-review

Abstract

A review of studies on DNA methylation in colonic neoplasia is presented. Hypomethylation of a wide variety of genes from throughout the genome was seen in all colon cancers studied. These changes preceded malignancy because benign adenomas were also affected.

Original languageEnglish (US)
Pages (from-to)149-151
Number of pages3
JournalSeminars in surgical oncology
Volume3
Issue number3
DOIs
StatePublished - 1987

Keywords

  • hypomethylation
  • molecular biology
  • polyps

ASJC Scopus subject areas

  • Surgery
  • Oncology

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