Alteration in connections between muscle and anterior horn motoneurons after peripheral nerve repair

Thomas Brushart, M. Marsel Mesulam

Research output: Contribution to journalArticle

Abstract

The connections between the spinal cord and lower leg muscles of the rat are significantly altered by repair of the intervening sciatic nerve. Muscles supplied by the peroneal branch of the sciatic are innervated by fewer motoneurons after sciatic repair. Many of these neurons originally innervated the peroneal muscles, and others formerly served the antagonistic tibial muscles. Perikarya in the size range of alpha motoneurons regained peripheral connections with greater frequency than those in the gamma range. There are thus postoperative defects in the extent and specificity of alpha reinnervation as well as in the degree of gamma control.

Original languageEnglish (US)
Pages (from-to)603-605
Number of pages3
JournalScience
Volume208
Issue number4444
StatePublished - 1980
Externally publishedYes

Fingerprint

Motor Neurons
Horns
Peripheral Nerves
Muscles
Sciatic Nerve
Leg
Spinal Cord
Neurons

ASJC Scopus subject areas

  • General

Cite this

Alteration in connections between muscle and anterior horn motoneurons after peripheral nerve repair. / Brushart, Thomas; Mesulam, M. Marsel.

In: Science, Vol. 208, No. 4444, 1980, p. 603-605.

Research output: Contribution to journalArticle

@article{a482ced9d6644877a7fa49325dbc1bd5,
title = "Alteration in connections between muscle and anterior horn motoneurons after peripheral nerve repair",
abstract = "The connections between the spinal cord and lower leg muscles of the rat are significantly altered by repair of the intervening sciatic nerve. Muscles supplied by the peroneal branch of the sciatic are innervated by fewer motoneurons after sciatic repair. Many of these neurons originally innervated the peroneal muscles, and others formerly served the antagonistic tibial muscles. Perikarya in the size range of alpha motoneurons regained peripheral connections with greater frequency than those in the gamma range. There are thus postoperative defects in the extent and specificity of alpha reinnervation as well as in the degree of gamma control.",
author = "Thomas Brushart and Mesulam, {M. Marsel}",
year = "1980",
language = "English (US)",
volume = "208",
pages = "603--605",
journal = "Science",
issn = "0036-8075",
publisher = "American Association for the Advancement of Science",
number = "4444",

}

TY - JOUR

T1 - Alteration in connections between muscle and anterior horn motoneurons after peripheral nerve repair

AU - Brushart, Thomas

AU - Mesulam, M. Marsel

PY - 1980

Y1 - 1980

N2 - The connections between the spinal cord and lower leg muscles of the rat are significantly altered by repair of the intervening sciatic nerve. Muscles supplied by the peroneal branch of the sciatic are innervated by fewer motoneurons after sciatic repair. Many of these neurons originally innervated the peroneal muscles, and others formerly served the antagonistic tibial muscles. Perikarya in the size range of alpha motoneurons regained peripheral connections with greater frequency than those in the gamma range. There are thus postoperative defects in the extent and specificity of alpha reinnervation as well as in the degree of gamma control.

AB - The connections between the spinal cord and lower leg muscles of the rat are significantly altered by repair of the intervening sciatic nerve. Muscles supplied by the peroneal branch of the sciatic are innervated by fewer motoneurons after sciatic repair. Many of these neurons originally innervated the peroneal muscles, and others formerly served the antagonistic tibial muscles. Perikarya in the size range of alpha motoneurons regained peripheral connections with greater frequency than those in the gamma range. There are thus postoperative defects in the extent and specificity of alpha reinnervation as well as in the degree of gamma control.

UR - http://www.scopus.com/inward/record.url?scp=0019313516&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0019313516&partnerID=8YFLogxK

M3 - Article

VL - 208

SP - 603

EP - 605

JO - Science

JF - Science

SN - 0036-8075

IS - 4444

ER -