Alpha-thalassemia: Prenatal diagnosis and neonatal implications

Mark C. Maberry; Victor R. Klein; Corinne Boehm; Tina C. Warren; Larry C. Gilstrap

doi:10.1055/s-2007-999522

Alpha-thalassemia: Prenatal diagnosis and neonatal implications

Mark C. Maberry, Victor R. Klein, Corinne Boehm, Tina C. Warren, Larry C. Gilstrap

School of Medicine

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Homozygous α-thalassemia major, or Bart's hemoglobinopathy, is the most common etiology of nonimmune hydrops in those of Oriental descent. The prenatal diagnosis can now be made utilizing DNA hybridization technique from fetal cells obtained by either amniocentesis or chorionic villus sampling. A case is reviewed documenting the utilization of DNA studies in managing patients known or suspected to have a history of α-thalassemia major.

Original language	English (US)
Pages (from-to)	356-358
Number of pages	3
Journal	American journal of perinatology
Volume	7
Issue number	4
DOIs	https://doi.org/10.1055/s-2007-999522
State	Published - Oct 1990

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Obstetrics and Gynecology

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10.1055/s-2007-999522

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title = "Alpha-thalassemia: Prenatal diagnosis and neonatal implications",

abstract = "Homozygous α-thalassemia major, or Bart's hemoglobinopathy, is the most common etiology of nonimmune hydrops in those of Oriental descent. The prenatal diagnosis can now be made utilizing DNA hybridization technique from fetal cells obtained by either amniocentesis or chorionic villus sampling. A case is reviewed documenting the utilization of DNA studies in managing patients known or suspected to have a history of α-thalassemia major.",

author = "Maberry, {Mark C.} and Klein, {Victor R.} and Corinne Boehm and Warren, {Tina C.} and Gilstrap, {Larry C.}",

year = "1990",

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T2 - Prenatal diagnosis and neonatal implications

AU - Maberry, Mark C.

AU - Klein, Victor R.

AU - Boehm, Corinne

AU - Warren, Tina C.

AU - Gilstrap, Larry C.

PY - 1990/10

Y1 - 1990/10

N2 - Homozygous α-thalassemia major, or Bart's hemoglobinopathy, is the most common etiology of nonimmune hydrops in those of Oriental descent. The prenatal diagnosis can now be made utilizing DNA hybridization technique from fetal cells obtained by either amniocentesis or chorionic villus sampling. A case is reviewed documenting the utilization of DNA studies in managing patients known or suspected to have a history of α-thalassemia major.

AB - Homozygous α-thalassemia major, or Bart's hemoglobinopathy, is the most common etiology of nonimmune hydrops in those of Oriental descent. The prenatal diagnosis can now be made utilizing DNA hybridization technique from fetal cells obtained by either amniocentesis or chorionic villus sampling. A case is reviewed documenting the utilization of DNA studies in managing patients known or suspected to have a history of α-thalassemia major.

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JF - American journal of perinatology

IS - 4

ER -

Alpha-thalassemia: Prenatal diagnosis and neonatal implications

Abstract

ASJC Scopus subject areas

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