Abstract
Clinical and laboratory studies of alpha fetoprotein (AFP) producing hepatomas demonstrated that: serum AFP levels correlated directly with tumor growth; circulating AFP could be cleared by passive administration of an excess of anti AFP; and highly specific anti AFP functioned as a carrier to localize diagnostic and possible therapeutic amounts of radioactivity in hepatoma tissue. These studies helped elucidate certain criteria which should be fulfilled before attempts to initiate passive humoral immunotherapy of cancer are undertaken.
Original language | English (US) |
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Pages (from-to) | 599-605 |
Number of pages | 7 |
Journal | Annals of surgery |
Volume | 180 |
Issue number | 4 |
DOIs | |
State | Published - 1974 |
ASJC Scopus subject areas
- Surgery