Allergen gene transfer

Shau Ku Huang, Kaw Yan Chua, Kue Hsiung Hsieh

Research output: Contribution to journalArticlepeer-review

Abstract

DNA-based immunization induces a biased Th1 immune response, and offers a novel strategy for modulation of the Th2-associated response. Recent studies have provided evidence that antigen-induced allergic responses can be modulated in rodents immunized with plasmid DNAs encoding the sensitizing antigens. Further understanding of the regulatory mechanism involved and optimization of gene transfer/expression systems will assist greatly in proving the clinical utility of this process.

Original languageEnglish (US)
Pages (from-to)800-804
Number of pages5
JournalCurrent Opinion in Immunology
Volume9
Issue number6
DOIs
StatePublished - Dec 1997

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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