Allergen gene transfer

Shau Ku Huang, Kaw Yan Chua, Kue Hsiung Hsieh

Research output: Contribution to journalArticle

Abstract

DNA-based immunization induces a biased Th1 immune response, and offers a novel strategy for modulation of the Th2-associated response. Recent studies have provided evidence that antigen-induced allergic responses can be modulated in rodents immunized with plasmid DNAs encoding the sensitizing antigens. Further understanding of the regulatory mechanism involved and optimization of gene transfer/expression systems will assist greatly in proving the clinical utility of this process.

Original languageEnglish (US)
Pages (from-to)800-804
Number of pages5
JournalCurrent Opinion in Immunology
Volume9
Issue number6
DOIs
StatePublished - Dec 1997

Fingerprint

Allergens
Antigens
DNA
Genes
Rodentia
Immunization
Plasmids
Gene Expression

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

Cite this

Huang, S. K., Chua, K. Y., & Hsieh, K. H. (1997). Allergen gene transfer. Current Opinion in Immunology, 9(6), 800-804. https://doi.org/10.1016/S0952-7915(97)80181-1

Allergen gene transfer. / Huang, Shau Ku; Chua, Kaw Yan; Hsieh, Kue Hsiung.

In: Current Opinion in Immunology, Vol. 9, No. 6, 12.1997, p. 800-804.

Research output: Contribution to journalArticle

Huang, SK, Chua, KY & Hsieh, KH 1997, 'Allergen gene transfer', Current Opinion in Immunology, vol. 9, no. 6, pp. 800-804. https://doi.org/10.1016/S0952-7915(97)80181-1
Huang, Shau Ku ; Chua, Kaw Yan ; Hsieh, Kue Hsiung. / Allergen gene transfer. In: Current Opinion in Immunology. 1997 ; Vol. 9, No. 6. pp. 800-804.
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