Alkaline phosphatase measurements of paired normal and osteosarcoma tissue culture lines obtained from the same patient

William Thorpe; Walter Loeb; Cornelia Hyatt; Steven A. Rosenberg

Alkaline phosphatase measurements of paired normal and osteosarcoma tissue culture lines obtained from the same patient

William Thorpe, Walter Loeb, Cornelia Hyatt, Steven A. Rosenberg

School of Medicine

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

Markedly different levels of alkaline phosphatase production have been found in paired osteosarcoma cells and normal skin fibroblasts grown in tissue culture from 12 patients with osteosarcoma. In all cases, the osteosarcoma line contains significantly more alkaline phosphatase than does the paired normal line from that same patient. These criteria may be useful in distinguishing osteosarcoma from normal fibroblast overgrowth in tissue culture.

Original language	English (US)
Pages (from-to)	277-279
Number of pages	3
Journal	Cancer Research
Volume	39
Issue number	1
State	Published - Jan 1 1979

ASJC Scopus subject areas

Oncology
Cancer Research

Cite this

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title = "Alkaline phosphatase measurements of paired normal and osteosarcoma tissue culture lines obtained from the same patient",

abstract = "Markedly different levels of alkaline phosphatase production have been found in paired osteosarcoma cells and normal skin fibroblasts grown in tissue culture from 12 patients with osteosarcoma. In all cases, the osteosarcoma line contains significantly more alkaline phosphatase than does the paired normal line from that same patient. These criteria may be useful in distinguishing osteosarcoma from normal fibroblast overgrowth in tissue culture.",

author = "William Thorpe and Walter Loeb and Cornelia Hyatt and Rosenberg, {Steven A.}",

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AU - Loeb, Walter

AU - Hyatt, Cornelia

AU - Rosenberg, Steven A.

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Y1 - 1979/1/1

N2 - Markedly different levels of alkaline phosphatase production have been found in paired osteosarcoma cells and normal skin fibroblasts grown in tissue culture from 12 patients with osteosarcoma. In all cases, the osteosarcoma line contains significantly more alkaline phosphatase than does the paired normal line from that same patient. These criteria may be useful in distinguishing osteosarcoma from normal fibroblast overgrowth in tissue culture.

AB - Markedly different levels of alkaline phosphatase production have been found in paired osteosarcoma cells and normal skin fibroblasts grown in tissue culture from 12 patients with osteosarcoma. In all cases, the osteosarcoma line contains significantly more alkaline phosphatase than does the paired normal line from that same patient. These criteria may be useful in distinguishing osteosarcoma from normal fibroblast overgrowth in tissue culture.

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Alkaline phosphatase measurements of paired normal and osteosarcoma tissue culture lines obtained from the same patient

Abstract

ASJC Scopus subject areas

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