Alkaline phosphatase measurements of paired normal and osteosarcoma tissue culture lines obtained from the same patient

William Thorpe, Walter Loeb, Cornelia Hyatt, Steven A. Rosenberg

Research output: Contribution to journalArticlepeer-review

Abstract

Markedly different levels of alkaline phosphatase production have been found in paired osteosarcoma cells and normal skin fibroblasts grown in tissue culture from 12 patients with osteosarcoma. In all cases, the osteosarcoma line contains significantly more alkaline phosphatase than does the paired normal line from that same patient. These criteria may be useful in distinguishing osteosarcoma from normal fibroblast overgrowth in tissue culture.

Original languageEnglish (US)
Pages (from-to)277-279
Number of pages3
JournalCancer Research
Volume39
Issue number1
StatePublished - Jan 1 1979

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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