Algorithms for calculating detector efficiency normalization coefficients for true coincidences in 3D PET

R. D. Badawi, M. A. Lodge, P. K. Marsden

Research output: Contribution to journalArticlepeer-review

35 Scopus citations


Accurate normalization of lines of response in 3D PET is a prerequisite for quantitative reconstruction. Most current methods are component based, calculating a series of geometric and intrinsic detector efficiency factors. We have reviewed the theory behind several existing algorithms for calculating detector efficiency factors in 2D and 3D PET, and have extended them to create a range of new algorithms. Three of the algorithms described are 'fully 3D' in that they make use of data from all detector rings for the calculation of the efficiencies of any one line of response. We have assessed the performance of the new and existing methods using simulated and real data, and have demonstrated that the fully 3D algorithms allow the rapid acquisition of crystal efficiency normalization data using low activity sources. Such methods enable the use of scatter free scanning line sources or the use of very short acquisitions of cylindrical sources for routine normalization.

Original languageEnglish (US)
Pages (from-to)189-205
Number of pages17
JournalPhysics in medicine and biology
Issue number1
StatePublished - 1998
Externally publishedYes

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging

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