Alcohol use and retinal vessels: Insights into the mechanism of alcohol-induced stroke

Michael John Klag, Richard D Moore, Yoshimichi Sakai, Sumio Sasaki, Richard W. Stone, George W. Comstock

Research output: Contribution to journalArticle

Abstract

Klag M J (The Johns Hopkins Hospital, 600 N Wolfe Street, Baltimore, Maryland 21205, USA), Moore R D, Sakai Y, Sasaki S, Stone R W and Comstock G W. Alcohol use and retinal vessels: insights into the mechanism of alcohol-induced stroke. International Journal of Epidemiology 1989, 18: 619-625.Alcohol use is a recognized risk factor for stroke. We hypothesized that alcohol use may increase the risk of stroke, independent of an effect on blood pressure, by causing cerebral vasoconstriction. To examine this, we used retinal vessels as a marker for cerebral vessels and analysed the cross-sectional associations between alcohol use and total retinal vessel width in 741 Japanese and 434 American white male telephone executives. Systolic and diastolic blood pressures were negatively associated with retinal vessel width in the Japanese (p

Original languageEnglish (US)
Pages (from-to)619-625
Number of pages7
JournalInternational Journal of Epidemiology
Volume18
Issue number3
DOIs
StatePublished - Sep 1989
Externally publishedYes

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Retinal Vessels
Alcohol
Stroke
Vessel
Alcohols
Blood pressure
Blood Pressure
Epidemiology
Baltimore
Risk Factors
Vasoconstriction
Telephone
Research and Development
Alcohol use

ASJC Scopus subject areas

  • Statistics, Probability and Uncertainty
  • Applied Mathematics
  • Physiology (medical)
  • Reproductive Medicine
  • Obstetrics and Gynecology
  • Epidemiology

Cite this

Alcohol use and retinal vessels : Insights into the mechanism of alcohol-induced stroke. / Klag, Michael John; Moore, Richard D; Sakai, Yoshimichi; Sasaki, Sumio; Stone, Richard W.; Comstock, George W.

In: International Journal of Epidemiology, Vol. 18, No. 3, 09.1989, p. 619-625.

Research output: Contribution to journalArticle

Klag, Michael John ; Moore, Richard D ; Sakai, Yoshimichi ; Sasaki, Sumio ; Stone, Richard W. ; Comstock, George W. / Alcohol use and retinal vessels : Insights into the mechanism of alcohol-induced stroke. In: International Journal of Epidemiology. 1989 ; Vol. 18, No. 3. pp. 619-625.
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