Alcohol, stem cells and cancer

Shoujun Gu, Bao Ngoc Nguyen, Shuyun Rao, Shulin Li, Kirti Shetty, Asif Rashid, Vivek Shukla, Chu Xia Deng, Lopa Mishra, Bibhuti Mishra

Research output: Contribution to journalReview article

Abstract

Dosage, gender, and genetic susceptibility to the effects of alcohol remained only partially elucidated. In this review, we summarize the current knowledge of the mechanisms underlying the role of alcohol in liver and gastrointestinal cancers. In addition, two recent pathways- DNA repair and TGF-β signaling which provide new insights into alcohol in the regulation of cancers and stem cells are also discussed here.

Original languageEnglish (US)
Pages (from-to)695-700
Number of pages6
JournalGenes and Cancer
Volume8
Issue number9-10
DOIs
StatePublished - Sep 2017

Keywords

  • Alcohol
  • Cancer
  • DNA repair
  • Stem cells
  • TGF-β

ASJC Scopus subject areas

  • Genetics
  • Cancer Research

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  • Cite this

    Gu, S., Nguyen, B. N., Rao, S., Li, S., Shetty, K., Rashid, A., Shukla, V., Deng, C. X., Mishra, L., & Mishra, B. (2017). Alcohol, stem cells and cancer. Genes and Cancer, 8(9-10), 695-700. https://doi.org/10.18632/genesandcancer.156