Alcohol intake and risk of breast cancer: The euramic study

M. A. Royo-Bordonada, J. M. Martín-Moreno, Eliseo Guallar, L. Gorgojo, P. Van't Veer, M. Mendez, J. K. Huttunen, B. C. Martin, A. F M Kardinaal, J. Fernández-Crehuet, M. Thamm, J. J. Strain, F. J. Kok, L. Kohlmeier

Research output: Contribution to journalArticle

Abstract

To evaluate the association of alcohol intake with the risk of breast cancer in post-menopausal women, we analyzed the data from an international case-control study conducted in five European countries (FRG, Switzerland, Northern Ireland, the Netherlands and Spain). Information on alcohol intake was available in 315 cases and 364 controls. Medians for the tertiles of alcohol intake among current drinkers were 1.7, 6.0, and 20.0 g/day. Adjusted relative risks (and 95% confidence intervals) of breast cancer for each tertile of intake in current drinkers, compared to never drinkers, were 1.00 (0.60-1.67), 1.01 (0.60-1.73), and 1.18 (0.69-2.03). The adjusted relative risk for ex-drinkers was 1.73 (1.07-2.79). Among both current drinkers and ex-drinkers, the relative risk was higher for those with body mass index above the median compared to those with body mass index below the median. These results do not support a dose-response effect of alcohol on breast cancer risk, although consumption levels were too low to exclude increased risk with high regular intake. Further research is necessary to evaluate the risk of developing breast cancer among ex-drinkers and the potential interaction between body mass index and alcohol drinking.

Original languageEnglish (US)
Pages (from-to)150-156
Number of pages7
JournalNeoplasma
Volume44
Issue number3
StatePublished - 1997
Externally publishedYes

Fingerprint

Alcohols
Breast Neoplasms
Body Mass Index
Northern Ireland
Switzerland
Alcohol Drinking
Netherlands
Spain
Case-Control Studies
Confidence Intervals
Research

Keywords

  • alcohol
  • breast cancer
  • case-control studies

ASJC Scopus subject areas

  • Cancer Research

Cite this

Royo-Bordonada, M. A., Martín-Moreno, J. M., Guallar, E., Gorgojo, L., Van't Veer, P., Mendez, M., ... Kohlmeier, L. (1997). Alcohol intake and risk of breast cancer: The euramic study. Neoplasma, 44(3), 150-156.

Alcohol intake and risk of breast cancer : The euramic study. / Royo-Bordonada, M. A.; Martín-Moreno, J. M.; Guallar, Eliseo; Gorgojo, L.; Van't Veer, P.; Mendez, M.; Huttunen, J. K.; Martin, B. C.; Kardinaal, A. F M; Fernández-Crehuet, J.; Thamm, M.; Strain, J. J.; Kok, F. J.; Kohlmeier, L.

In: Neoplasma, Vol. 44, No. 3, 1997, p. 150-156.

Research output: Contribution to journalArticle

Royo-Bordonada, MA, Martín-Moreno, JM, Guallar, E, Gorgojo, L, Van't Veer, P, Mendez, M, Huttunen, JK, Martin, BC, Kardinaal, AFM, Fernández-Crehuet, J, Thamm, M, Strain, JJ, Kok, FJ & Kohlmeier, L 1997, 'Alcohol intake and risk of breast cancer: The euramic study', Neoplasma, vol. 44, no. 3, pp. 150-156.
Royo-Bordonada MA, Martín-Moreno JM, Guallar E, Gorgojo L, Van't Veer P, Mendez M et al. Alcohol intake and risk of breast cancer: The euramic study. Neoplasma. 1997;44(3):150-156.
Royo-Bordonada, M. A. ; Martín-Moreno, J. M. ; Guallar, Eliseo ; Gorgojo, L. ; Van't Veer, P. ; Mendez, M. ; Huttunen, J. K. ; Martin, B. C. ; Kardinaal, A. F M ; Fernández-Crehuet, J. ; Thamm, M. ; Strain, J. J. ; Kok, F. J. ; Kohlmeier, L. / Alcohol intake and risk of breast cancer : The euramic study. In: Neoplasma. 1997 ; Vol. 44, No. 3. pp. 150-156.
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