Alcohol consumption as a cofactor in the progression of HIV infection and AIDS

Lili Penkower; Mary Amanda Dew; Lawrence Kingsley; Susan Y. Zhou; Constantine G. Lyketsos; Jerry Wesch; J. Walton Senterfitt; Donald R. Hoover; James T. Becker

doi:10.1016/0741-8329(95)00042-9

Alcohol consumption as a cofactor in the progression of HIV infection and AIDS

Lili Penkower, Mary Amanda Dew, Lawrence Kingsley, Susan Y. Zhou, Constantine G. Lyketsos, Jerry Wesch, J. Walton Senterfitt, Donald R. Hoover, James T. Becker

School of Medicine

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

Abstract

Alcohol consumption as a cofactor in the progression of HIV infection was examined in 1446 homosexual and bisexual HIV + men enrolled in the Multicenter AIDS Cohort Study who had a minimum of three visits. Two measures of drinking were employed: initial level, and pattern during the study period. Outcome measures included AIDS-related symptoms and AIDS diagnosis. Level of drinking at entry to the study was not significantly associated with either AIDS-related symptoms at final visit or with AIDS diagnosis. However, men who decreased drinking were more likely to report thrush, fatigue, weight loss, and diarrhea at their final visit. Most likely, these men decreased drinking as a result of failing health, not because their drinking pattern influenced symptom onset. These data support earlier reports that found no relationship between alcohol consumption and progression to AIDS.

Original language	English (US)
Pages (from-to)	547-552
Number of pages	6
Journal	Alcohol
Volume	12
Issue number	6
DOIs	https://doi.org/10.1016/0741-8329(95)00042-9
State	Published - 1995

Keywords

AIDS
Alcohol
HIV

ASJC Scopus subject areas

Health(social science)
Biochemistry
Toxicology
Neurology
Behavioral Neuroscience

Access to Document

10.1016/0741-8329(95)00042-9

Cite this

@article{7bfdd455e74c4cfe93c2df7236840f11,

title = "Alcohol consumption as a cofactor in the progression of HIV infection and AIDS",

abstract = "Alcohol consumption as a cofactor in the progression of HIV infection was examined in 1446 homosexual and bisexual HIV + men enrolled in the Multicenter AIDS Cohort Study who had a minimum of three visits. Two measures of drinking were employed: initial level, and pattern during the study period. Outcome measures included AIDS-related symptoms and AIDS diagnosis. Level of drinking at entry to the study was not significantly associated with either AIDS-related symptoms at final visit or with AIDS diagnosis. However, men who decreased drinking were more likely to report thrush, fatigue, weight loss, and diarrhea at their final visit. Most likely, these men decreased drinking as a result of failing health, not because their drinking pattern influenced symptom onset. These data support earlier reports that found no relationship between alcohol consumption and progression to AIDS.",

keywords = "AIDS, Alcohol, HIV",

author = "Lili Penkower and Dew, {Mary Amanda} and Lawrence Kingsley and Zhou, {Susan Y.} and Lyketsos, {Constantine G.} and Jerry Wesch and Senterfitt, {J. Walton} and Hoover, {Donald R.} and Becker, {James T.}",

year = "1995",

doi = "10.1016/0741-8329(95)00042-9",

language = "English (US)",

volume = "12",

pages = "547--552",

journal = "Alcohol",

issn = "0741-8329",

publisher = "Elsevier Inc.",

number = "6",

}

TY - JOUR

T1 - Alcohol consumption as a cofactor in the progression of HIV infection and AIDS

AU - Penkower, Lili

AU - Dew, Mary Amanda

AU - Kingsley, Lawrence

AU - Zhou, Susan Y.

AU - Lyketsos, Constantine G.

AU - Wesch, Jerry

AU - Senterfitt, J. Walton

AU - Hoover, Donald R.

AU - Becker, James T.

PY - 1995

Y1 - 1995

N2 - Alcohol consumption as a cofactor in the progression of HIV infection was examined in 1446 homosexual and bisexual HIV + men enrolled in the Multicenter AIDS Cohort Study who had a minimum of three visits. Two measures of drinking were employed: initial level, and pattern during the study period. Outcome measures included AIDS-related symptoms and AIDS diagnosis. Level of drinking at entry to the study was not significantly associated with either AIDS-related symptoms at final visit or with AIDS diagnosis. However, men who decreased drinking were more likely to report thrush, fatigue, weight loss, and diarrhea at their final visit. Most likely, these men decreased drinking as a result of failing health, not because their drinking pattern influenced symptom onset. These data support earlier reports that found no relationship between alcohol consumption and progression to AIDS.

AB - Alcohol consumption as a cofactor in the progression of HIV infection was examined in 1446 homosexual and bisexual HIV + men enrolled in the Multicenter AIDS Cohort Study who had a minimum of three visits. Two measures of drinking were employed: initial level, and pattern during the study period. Outcome measures included AIDS-related symptoms and AIDS diagnosis. Level of drinking at entry to the study was not significantly associated with either AIDS-related symptoms at final visit or with AIDS diagnosis. However, men who decreased drinking were more likely to report thrush, fatigue, weight loss, and diarrhea at their final visit. Most likely, these men decreased drinking as a result of failing health, not because their drinking pattern influenced symptom onset. These data support earlier reports that found no relationship between alcohol consumption and progression to AIDS.

KW - AIDS

KW - Alcohol

KW - HIV

UR - http://www.scopus.com/inward/record.url?scp=0028834719&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028834719&partnerID=8YFLogxK

U2 - 10.1016/0741-8329(95)00042-9

DO - 10.1016/0741-8329(95)00042-9

M3 - Article

C2 - 8590617

AN - SCOPUS:0028834719

SN - 0741-8329

VL - 12

SP - 547

EP - 552

JO - Alcohol

JF - Alcohol

IS - 6

ER -

Alcohol consumption as a cofactor in the progression of HIV infection and AIDS

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this