Albuminuria and estimated glomerular filtration rate independently associate with acute kidney injury

Morgan Grams, Brad C. Astor, Lori D. Bash, Kunihiro Matsushita, Yaping Wang, Josef Coresh

Research output: Contribution to journalArticle

Abstract

Acute kidney injury (AKI) is increasingly common and a significant contributor to excess death in hospitalized patients. CKD is an established risk factor for AKI; however, the independent graded association of urine albumin excretion with AKI is unknown. We analyzed a prospective cohort of 11,200 participants in the Atherosclerosis Risk in Communities (ARIC) study for the association between baseline urine albumin-to-creatinine ratio and estimated GFR (eGFR) with hospitalizations or death with AKI. The incidence of AKI events was 4.0 per 1000 person-years of follow-up. Using participants with urine albumin-to-creatinine ratios

Original languageEnglish (US)
Pages (from-to)1757-1764
Number of pages8
JournalJournal of the American Society of Nephrology
Volume21
Issue number10
DOIs
StatePublished - 2010

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Albuminuria
Glomerular Filtration Rate
Acute Kidney Injury
Albumins
Urine
Creatinine
Atherosclerosis
Hospitalization
Incidence

ASJC Scopus subject areas

  • Nephrology
  • Medicine(all)

Cite this

Albuminuria and estimated glomerular filtration rate independently associate with acute kidney injury. / Grams, Morgan; Astor, Brad C.; Bash, Lori D.; Matsushita, Kunihiro; Wang, Yaping; Coresh, Josef.

In: Journal of the American Society of Nephrology, Vol. 21, No. 10, 2010, p. 1757-1764.

Research output: Contribution to journalArticle

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AU - Coresh, Josef

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