Alagille syndrome: Prenatal diagnosis and pregnancy outcome

Ferah Albayram; Kristyne Stone; David Nagey; Kathleen B. Schwarz; Karin Blakemore

doi:10.1159/000048035

Alagille syndrome: Prenatal diagnosis and pregnancy outcome

Ferah Albayram, Kristyne Stone, David Nagey, Kathleen B. Schwarz, Karin Blakemore

School of Medicine

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Abstract

The Alagille syndrome (AGS) is a multisystem autosomal dominant condition. In this case report, we describe a pregnant woman with this unusual disorder, in whom serial fetal sonography revealed severe pulmonary stenosis and progressively severe intrauterine growth retardation, suggesting that the fetus also had AGS, a diagnosis which was confirmed postnatally. In this report, the potential complications for pregnancy, labor and delivery when both mother and fetus are affected with AGS are described.

Original language	English (US)
Pages (from-to)	182-184
Number of pages	3
Journal	Fetal Diagnosis and Therapy
Volume	17
Issue number	3
DOIs	https://doi.org/10.1159/000048035
State	Published - 2002

Keywords

Alagille syndrome
JAGGED 1
Prenatal diagnosis

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Embryology
Radiology Nuclear Medicine and imaging
Obstetrics and Gynecology

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10.1159/000048035

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AU - Schwarz, Kathleen B.

AU - Blakemore, Karin

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AB - The Alagille syndrome (AGS) is a multisystem autosomal dominant condition. In this case report, we describe a pregnant woman with this unusual disorder, in whom serial fetal sonography revealed severe pulmonary stenosis and progressively severe intrauterine growth retardation, suggesting that the fetus also had AGS, a diagnosis which was confirmed postnatally. In this report, the potential complications for pregnancy, labor and delivery when both mother and fetus are affected with AGS are described.

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Alagille syndrome: Prenatal diagnosis and pregnancy outcome

Abstract

Keywords

ASJC Scopus subject areas

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