Alagille syndrome: Prenatal diagnosis and pregnancy outcome

Ferah Albayram, Kristyne Stone, David Nagey, Kathleen Schwarz, Karin Blakemore

Research output: Contribution to journalArticle

Abstract

The Alagille syndrome (AGS) is a multisystem autosomal dominant condition. In this case report, we describe a pregnant woman with this unusual disorder, in whom serial fetal sonography revealed severe pulmonary stenosis and progressively severe intrauterine growth retardation, suggesting that the fetus also had AGS, a diagnosis which was confirmed postnatally. In this report, the potential complications for pregnancy, labor and delivery when both mother and fetus are affected with AGS are described.

Original languageEnglish (US)
Pages (from-to)182-184
Number of pages3
JournalFetal Diagnosis and Therapy
Volume17
Issue number3
DOIs
StatePublished - 2002

Fingerprint

Alagille Syndrome
Pregnancy Outcome
Prenatal Diagnosis
Fetus
Obstetric Labor Complications
Prenatal Ultrasonography
Pulmonary Valve Stenosis
Fetal Growth Retardation
Pregnancy Complications
Pregnant Women
Mothers

Keywords

  • Alagille syndrome
  • JAGGED 1
  • Prenatal diagnosis

ASJC Scopus subject areas

  • Obstetrics and Gynecology
  • Pediatrics, Perinatology, and Child Health

Cite this

Alagille syndrome : Prenatal diagnosis and pregnancy outcome. / Albayram, Ferah; Stone, Kristyne; Nagey, David; Schwarz, Kathleen; Blakemore, Karin.

In: Fetal Diagnosis and Therapy, Vol. 17, No. 3, 2002, p. 182-184.

Research output: Contribution to journalArticle

Albayram, Ferah ; Stone, Kristyne ; Nagey, David ; Schwarz, Kathleen ; Blakemore, Karin. / Alagille syndrome : Prenatal diagnosis and pregnancy outcome. In: Fetal Diagnosis and Therapy. 2002 ; Vol. 17, No. 3. pp. 182-184.
@article{13c99d55d92a400d8d3daae7fbac3a97,
title = "Alagille syndrome: Prenatal diagnosis and pregnancy outcome",
abstract = "The Alagille syndrome (AGS) is a multisystem autosomal dominant condition. In this case report, we describe a pregnant woman with this unusual disorder, in whom serial fetal sonography revealed severe pulmonary stenosis and progressively severe intrauterine growth retardation, suggesting that the fetus also had AGS, a diagnosis which was confirmed postnatally. In this report, the potential complications for pregnancy, labor and delivery when both mother and fetus are affected with AGS are described.",
keywords = "Alagille syndrome, JAGGED 1, Prenatal diagnosis",
author = "Ferah Albayram and Kristyne Stone and David Nagey and Kathleen Schwarz and Karin Blakemore",
year = "2002",
doi = "10.1159/000048035",
language = "English (US)",
volume = "17",
pages = "182--184",
journal = "Fetal Diagnosis and Therapy",
issn = "1015-3837",
publisher = "S. Karger AG",
number = "3",

}

TY - JOUR

T1 - Alagille syndrome

T2 - Prenatal diagnosis and pregnancy outcome

AU - Albayram, Ferah

AU - Stone, Kristyne

AU - Nagey, David

AU - Schwarz, Kathleen

AU - Blakemore, Karin

PY - 2002

Y1 - 2002

N2 - The Alagille syndrome (AGS) is a multisystem autosomal dominant condition. In this case report, we describe a pregnant woman with this unusual disorder, in whom serial fetal sonography revealed severe pulmonary stenosis and progressively severe intrauterine growth retardation, suggesting that the fetus also had AGS, a diagnosis which was confirmed postnatally. In this report, the potential complications for pregnancy, labor and delivery when both mother and fetus are affected with AGS are described.

AB - The Alagille syndrome (AGS) is a multisystem autosomal dominant condition. In this case report, we describe a pregnant woman with this unusual disorder, in whom serial fetal sonography revealed severe pulmonary stenosis and progressively severe intrauterine growth retardation, suggesting that the fetus also had AGS, a diagnosis which was confirmed postnatally. In this report, the potential complications for pregnancy, labor and delivery when both mother and fetus are affected with AGS are described.

KW - Alagille syndrome

KW - JAGGED 1

KW - Prenatal diagnosis

UR - http://www.scopus.com/inward/record.url?scp=0036210431&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0036210431&partnerID=8YFLogxK

U2 - 10.1159/000048035

DO - 10.1159/000048035

M3 - Article

C2 - 11914573

AN - SCOPUS:0036210431

VL - 17

SP - 182

EP - 184

JO - Fetal Diagnosis and Therapy

JF - Fetal Diagnosis and Therapy

SN - 1015-3837

IS - 3

ER -