Abstract
Most hyperpolarized gas MRI, involving dynamic imaging of the human lungs, requires specialized ultra-fast MRI pulse sequences or the necessity for multiple breaths of hyperpolarized helium. Thus, most current dynamic imaging techniques are not ideal for a clinical setting. By using a standard Fast GRE pulse sequence on a GE Signa 1.5 T clinical MRI scanner outfitted with heterodyne functionality, we have developed a clinically feasible method for dynamic human lung imaging of the airways. The technique presented here exploits the non-renewability of hyperpolarized gas to achieve the first distal human airway images with up to 7th generation resolution of airways. Additionally, this approach requires only a single inspiration of hyperpolarized helium. The airway images achieved may provide unique information about possible causes of pulmonary airway constriction diseases.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 923-924 |
| Number of pages | 2 |
| Journal | Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings |
| Volume | 2 |
| State | Published - 2002 |
| Externally published | Yes |
| Event | Proceedings of the 2002 IEEE Engineering in Medicine and Biology 24th Annual Conference and the 2002 Fall Meeting of the Biomedical Engineering Society (BMES / EMBS) - Houston, TX, United States Duration: Oct 23 2002 → Oct 26 2002 |
Keywords
- Hyperpolarized gas
- MRI
- Pulmonary imaging
ASJC Scopus subject areas
- Signal Processing
- Biomedical Engineering
- Computer Vision and Pattern Recognition
- Health Informatics