TY - JOUR
T1 - Air pollution and mortality in Philadelphia, 1974-1988
AU - Kelsall, J. E.
AU - Samet, Jonathan M.
AU - Zeger, S. L.
AU - Xu, J.
N1 - Funding Information:
Research described in this article was conducted under contract to the Health Effects Institute (HEI), an organization jointly funded by the Environmental Protection Institute (EPA R824835) and automotive manufacturers. The contents of this article do not necessarily reflect the views and policies of HEI, nor do they necessarily reflect the views and policies of EPA, or motor vehicles or engine manufacturers. The authors wish to thank James Greenbaum for his technical contributions.
PY - 1997
Y1 - 1997
N2 - Analyses involving data from many locations throughout the world have now been conducted to assess the association between air pollution and mortality. To date, six independent analyses of mortality data for Philadelphia, Pennsylvania, have been reported. In this new analysis of Philadelphia data for 1974-1988, Poisson regression models were developed to estimate the increased risk of daily mortality associated with air pollution while controlling for longer-term time trends and season and for weather. Model development was based on prior understanding of the effects of these factors on mortality and on consideration of model fit. The authors found moderate correlations of daily concentrations of total suspended particles (TSP), sulfur dioxide (SO2), nitrogen dioxide (NO2), and carbon monoxide (CO), and only slight correlations of ozone (O3) with other pollutants. When included individually in the model, the means of current and previous days' levels of TSP, SO2, and O3 had statistically significant effects on total mortality; pollutant increases of an interquartile range (34.5 μg/m3, 12.9 ppb, and 20.2 ppb, respectively) were associated with increases in mortality of around 1% for TSP and SO2, and of around 2% for O3. The effects of TSP and SO2 were diminished when both pollutants were simultaneously included in the model, whether pairwise or in the full multi-pollutant model. These analyses confirm the association between TSP and mortality found in previous studies in Philadelphia and show that the association is robust to consideration of other pollutants in the model.
AB - Analyses involving data from many locations throughout the world have now been conducted to assess the association between air pollution and mortality. To date, six independent analyses of mortality data for Philadelphia, Pennsylvania, have been reported. In this new analysis of Philadelphia data for 1974-1988, Poisson regression models were developed to estimate the increased risk of daily mortality associated with air pollution while controlling for longer-term time trends and season and for weather. Model development was based on prior understanding of the effects of these factors on mortality and on consideration of model fit. The authors found moderate correlations of daily concentrations of total suspended particles (TSP), sulfur dioxide (SO2), nitrogen dioxide (NO2), and carbon monoxide (CO), and only slight correlations of ozone (O3) with other pollutants. When included individually in the model, the means of current and previous days' levels of TSP, SO2, and O3 had statistically significant effects on total mortality; pollutant increases of an interquartile range (34.5 μg/m3, 12.9 ppb, and 20.2 ppb, respectively) were associated with increases in mortality of around 1% for TSP and SO2, and of around 2% for O3. The effects of TSP and SO2 were diminished when both pollutants were simultaneously included in the model, whether pairwise or in the full multi-pollutant model. These analyses confirm the association between TSP and mortality found in previous studies in Philadelphia and show that the association is robust to consideration of other pollutants in the model.
KW - Air pollution
KW - Mortality
KW - Ozone
KW - Weather
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U2 - 10.1093/oxfordjournals.aje.a009351
DO - 10.1093/oxfordjournals.aje.a009351
M3 - Article
C2 - 9366623
AN - SCOPUS:0030832775
SN - 0002-9262
VL - 146
SP - 750
EP - 762
JO - American journal of epidemiology
JF - American journal of epidemiology
IS - 9
ER -