AIDS dementia complex with generalized myoclonus

John Maher, Shujeel Choudhri, William Halliday, Christopher Power, Avindra Nath

Research output: Contribution to journalArticlepeer-review

23 Scopus citations


Focal and segmental, but not generalized, myoclonus have been described with human immunodeficiency virus (HIV) infection. We describe three patients with generalized myoclonus and acquired immunodeficiency syndrome (AIDS) dementia complex. In each, myoclonus persisted until death, invariably after a course of a few months. In two patients, myoclonus was elicited by sudden auditory stimuli and resembled a startle response. This form of myoclonus may be subcortical in origin. We suggest that the AlDS dementia complex be included among the causes of myoclonic dementia.

Original languageEnglish (US)
Pages (from-to)593-597
Number of pages5
JournalMovement Disorders
Issue number4
StatePublished - Aug 14 1997


  • AIDS
  • Dementia
  • Encephalitis
  • HIV
  • Myoclonus

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology


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