Ahead of the curve: Mitochondrial fusion and phospholipase D

Robert E. Jensen, Hiromi Sesaki

Research output: Contribution to journalArticle

Abstract

A new study has identified a novel phospholipase D (PLD) that is located in the mitochondrial outer membrane and is required for organelle fusion. As PLD-catalysed production of fusogenic lipids is critical for many examples of membrane fusion (such as those mediated by SNAREs), this startling finding raises the possibility that mitochondria use a mechanism common to other cellular fusion events.

Original languageEnglish (US)
Pages (from-to)1215-1217
Number of pages3
JournalNature cell biology
Volume8
Issue number11
DOIs
StatePublished - Nov 1 2006

ASJC Scopus subject areas

  • Cell Biology

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