A new study has identified a novel phospholipase D (PLD) that is located in the mitochondrial outer membrane and is required for organelle fusion. As PLD-catalysed production of fusogenic lipids is critical for many examples of membrane fusion (such as those mediated by SNAREs), this startling finding raises the possibility that mitochondria use a mechanism common to other cellular fusion events.
|Original language||English (US)|
|Number of pages||3|
|Journal||Nature cell biology|
|State||Published - Nov 1 2006|
ASJC Scopus subject areas
- Cell Biology