TY - JOUR
T1 - Aging of the Cardiovascular System
AU - Weisfeldt, Myron L.
PY - 1980/11/13
Y1 - 1980/11/13
N2 - Recent studies have shown that aging has a selective effect on specific aspects of cardiovascular function and on the response to pharmacologic agents. Basal contractile function is well maintained in both isolated cardiac muscle1 and intact hearts from senescent animals, 2 although the relaxation phase of contraction is prolonged.3,4 In human beings, echocardiographic indexes of systolic left ventricular function at rest are unchanged with age in either the presence or absence of beta-adrenergic blockade.5,6 Thus, it is not surprising that Port and his colleagues, in their study published in this issue, found no age-associated change in radionuclide measurements of left ventricular.
AB - Recent studies have shown that aging has a selective effect on specific aspects of cardiovascular function and on the response to pharmacologic agents. Basal contractile function is well maintained in both isolated cardiac muscle1 and intact hearts from senescent animals, 2 although the relaxation phase of contraction is prolonged.3,4 In human beings, echocardiographic indexes of systolic left ventricular function at rest are unchanged with age in either the presence or absence of beta-adrenergic blockade.5,6 Thus, it is not surprising that Port and his colleagues, in their study published in this issue, found no age-associated change in radionuclide measurements of left ventricular.
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U2 - 10.1056/NEJM198011133032009
DO - 10.1056/NEJM198011133032009
M3 - Editorial
C2 - 7421933
AN - SCOPUS:0019199111
SN - 0028-4793
VL - 303
SP - 1172
EP - 1174
JO - New England Journal of Medicine
JF - New England Journal of Medicine
IS - 20
ER -