Aging effects on memory encoding in the frontal lobes

Glenn T. Stebbins, Maria C. Carrillo, Jennifer Dorfman, Courtney Dirksen, John Desmond, David A. Turner, David A. Bennett, Robert S. Wilson, Gary Glover, John D E Gabrieli

Research output: Contribution to journalArticle

Abstract

Functional magnetic resonance imaging (fMRI) was used to compare frontal-lobe activation in younger and older adults during encoding of words into memory. Participants made semantic or nonsemantic judgments about words. Younger adults exhibited greater activation for semantic relative to nonsemantic judgments in several regions, with the largest activation in the left inferior frontal gyrus. Older adults exhibited greater activation for semantic judgments in the same regions, but the extent of activation was reduced in left prefrontal regions. In older adults, there was a significant association between behavioral tests of declarative and working memory and extent of frontal activation. These results suggest that age-associated decreases in memory ability may be due to decreased frontal-lobe contributions to the initial encoding of experience.

Original languageEnglish (US)
Pages (from-to)44-55
Number of pages12
JournalPsychology and Aging
Volume17
Issue number1
DOIs
StatePublished - 2002
Externally publishedYes

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Frontal Lobe
Semantics
Young Adult
Aptitude
Prefrontal Cortex
Short-Term Memory
Magnetic Resonance Imaging

ASJC Scopus subject areas

  • Aging
  • Psychiatry and Mental health
  • Developmental and Educational Psychology
  • Experimental and Cognitive Psychology

Cite this

Stebbins, G. T., Carrillo, M. C., Dorfman, J., Dirksen, C., Desmond, J., Turner, D. A., ... Gabrieli, J. D. E. (2002). Aging effects on memory encoding in the frontal lobes. Psychology and Aging, 17(1), 44-55. https://doi.org/10.1037//0882-7974.17.1.44

Aging effects on memory encoding in the frontal lobes. / Stebbins, Glenn T.; Carrillo, Maria C.; Dorfman, Jennifer; Dirksen, Courtney; Desmond, John; Turner, David A.; Bennett, David A.; Wilson, Robert S.; Glover, Gary; Gabrieli, John D E.

In: Psychology and Aging, Vol. 17, No. 1, 2002, p. 44-55.

Research output: Contribution to journalArticle

Stebbins, GT, Carrillo, MC, Dorfman, J, Dirksen, C, Desmond, J, Turner, DA, Bennett, DA, Wilson, RS, Glover, G & Gabrieli, JDE 2002, 'Aging effects on memory encoding in the frontal lobes', Psychology and Aging, vol. 17, no. 1, pp. 44-55. https://doi.org/10.1037//0882-7974.17.1.44
Stebbins GT, Carrillo MC, Dorfman J, Dirksen C, Desmond J, Turner DA et al. Aging effects on memory encoding in the frontal lobes. Psychology and Aging. 2002;17(1):44-55. https://doi.org/10.1037//0882-7974.17.1.44
Stebbins, Glenn T. ; Carrillo, Maria C. ; Dorfman, Jennifer ; Dirksen, Courtney ; Desmond, John ; Turner, David A. ; Bennett, David A. ; Wilson, Robert S. ; Glover, Gary ; Gabrieli, John D E. / Aging effects on memory encoding in the frontal lobes. In: Psychology and Aging. 2002 ; Vol. 17, No. 1. pp. 44-55.
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