Aggregative Escherichia coli, Salmonella, and Shigella are associated with increasing duration of diarrhea

M. K. Bhan, S. Sazawal, P. Raj, N. Bhandari, R. Kumar, Y. Bhardwaj, R. Shrivastava, S. Bhatnagar

Research output: Contribution to journalArticlepeer-review

Abstract

In order to relate etiology of diarrhea to the duration of the episode, a cohort of 452 children upto 36 months of age was visited once weekly at their households for 18 consecutive months to record diarrheal morbidity. Fecal specimens were obtained in 453 diarrheal episodes occurring in 354 children during this period. The common putative agents as single isolations associated with diarrhea were EA-AggEC (17·2%), ETEC (14·1%), EPEC (6·0%) and rotavirus (4·0%). The pathogens with higher median duration of diarrhea were Shigella (13·5; mean ±SD 13·7±2·7), Salmonella (8·8: 15·3±4·5) and EA=AggEC (12·0: 15·1 ±1·8). Of 55 episodes with duration of >14 days, the main pathogens isolated were EA-AggEC (32·7%), ETEC (9·0), Salmonella, G. lambia (5·5% each) and Shigella (3·5%). These data provide a preliminary evidence to suggest that EA-AggEC may well be the main long sought microbial agent responsible for diarrhea of long duration.

Original languageEnglish (US)
Pages (from-to)81-86
Number of pages6
JournalThe Indian Journal of Pediatrics
Volume56
Issue number1
DOIs
StatePublished - Jan 1 1989

Keywords

  • Diarrhea
  • Diarrhea complications
  • Diarrhea infantile E. coli

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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