Age-related effects on symptom status and health-related quality of life in persons with HIV/AIDS

Kathleen M. Nokes, Christopher Lance Coleman, Mary Jane Hamilton, Inge B. Corless, Elizabeth Sefcik, Kenn M. Kirksey, Lucille Sanzero Eller, Jeanne Kemppainen, Pamela J. Dole, Patrice K. Nicholas, Nancy R. Reynolds, Eli Haugen Bunch, William L. Holzemer, Dean J. Wantland, Yun Fang Tsai, Marta Rivero-Mendez, Gladys E. Canaval

Research output: Contribution to journalArticlepeer-review

19 Scopus citations


Health-related quality of life (HRQOL) is linked to symptom status and may be related to age in HIV-positive persons. Data were collected in a multisite HIV-positive sample (N = 1,217) using an HIV-specific HRQOL and three symptom status instruments according to the Wilson and Cleary HRQOL model. Multiple stepwise linear regression analysis found that younger age predicted higher sexual function (delta;R2 = 12, p < .01) and older age predicted greater provider trust (delta;R2 = 04, p < .01). No significant differences were found in symptom status or the other seven HRQOL dimensions. Although older HIV-positive persons reported more comorbidities, they did not report more symptoms.

Original languageEnglish (US)
Pages (from-to)10-16
Number of pages7
JournalApplied Nursing Research
Issue number1
StatePublished - Feb 2011
Externally publishedYes

ASJC Scopus subject areas

  • Nursing(all)


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