Aerosolized vancomycin therapy facilitating nursing home placement

J. D. Gradon, E. H. Wu, L. I. Lutwick

Research output: Contribution to journalArticle

Abstract

Objective: To demonstrate a novel method of eliminating nasopharyngeal colonization by methicillin-resistant Staphylococcus aureus (MRSA) in a debilitated, hospitalized patient. Design: Single-patient, nonblind, nonplacebo, case study. Setting: Community hospital, Brooklyn, NY. Patient: Hospitalized patient with recalcitrant nasopharyngeal MRSA colonization that could not be eliminated by conventional therapeutic interventions. Interventions: Aerosolized vancomycin hydrochloride 120 mg q6h administered in room air via face mask together with vancomycin nasal drops, 2 drops to each nostril q6h. Main Outcome Measure: Elimination of MRSA from the nasopharynx of the patient. Results: Successful elimination of MRSA colonization after four days of therapy. Conclusions: Aerosolized vancomycin in combination with vancomycin nasal drops is beneficial in eliminating nasopharyngeal colonization by MRSA. Clinical trials are warranted to confirm this clinical observation.

Original languageEnglish (US)
Pages (from-to)209-210
Number of pages2
JournalAnnals of Pharmacotherapy
Volume26
Issue number2
StatePublished - 1992
Externally publishedYes

Fingerprint

Vancomycin
Methicillin-Resistant Staphylococcus aureus
Nursing Homes
Nose
Therapeutics
Nasopharynx
Community Hospital
Masks
Air
Observation
Outcome Assessment (Health Care)
Clinical Trials

ASJC Scopus subject areas

  • Pharmacology (medical)
  • Pharmacology, Toxicology and Pharmaceutics(all)

Cite this

Gradon, J. D., Wu, E. H., & Lutwick, L. I. (1992). Aerosolized vancomycin therapy facilitating nursing home placement. Annals of Pharmacotherapy, 26(2), 209-210.

Aerosolized vancomycin therapy facilitating nursing home placement. / Gradon, J. D.; Wu, E. H.; Lutwick, L. I.

In: Annals of Pharmacotherapy, Vol. 26, No. 2, 1992, p. 209-210.

Research output: Contribution to journalArticle

Gradon, JD, Wu, EH & Lutwick, LI 1992, 'Aerosolized vancomycin therapy facilitating nursing home placement', Annals of Pharmacotherapy, vol. 26, no. 2, pp. 209-210.
Gradon, J. D. ; Wu, E. H. ; Lutwick, L. I. / Aerosolized vancomycin therapy facilitating nursing home placement. In: Annals of Pharmacotherapy. 1992 ; Vol. 26, No. 2. pp. 209-210.
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