Advances in the Management of Central Nervous System Infections in the ICU

Wendy C. Ziai; John J. Lewin

doi:10.1016/j.ccc.2006.11.009

Advances in the Management of Central Nervous System Infections in the ICU

Wendy C. Ziai, John J. Lewin

School of Medicine

Research output: Contribution to journal › Review article › peer-review

18 Scopus citations

Abstract

The management of patients who have CNS infections is challenging. Therapy for CNS infections is evolving in light of changing microbial resistance patterns and with the introduction of new antimicrobial agents. Knowledge of cerebral inflammation, molecular diagnostics, and the evolving microbial epidemiology are important to optimizing therapy in patients with meningitis. Future investigations into the role of selective immunomodulation and other neuroprotective strategies may lead to significant advances in the management of CNS infection.

Original language	English (US)
Pages (from-to)	661-694
Number of pages	34
Journal	Critical care clinics
Volume	22
Issue number	4
DOIs	https://doi.org/10.1016/j.ccc.2006.11.009
State	Published - Oct 2006

ASJC Scopus subject areas

Critical Care and Intensive Care Medicine

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10.1016/j.ccc.2006.11.009

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title = "Advances in the Management of Central Nervous System Infections in the ICU",

abstract = "The management of patients who have CNS infections is challenging. Therapy for CNS infections is evolving in light of changing microbial resistance patterns and with the introduction of new antimicrobial agents. Knowledge of cerebral inflammation, molecular diagnostics, and the evolving microbial epidemiology are important to optimizing therapy in patients with meningitis. Future investigations into the role of selective immunomodulation and other neuroprotective strategies may lead to significant advances in the management of CNS infection.",

author = "Ziai, {Wendy C.} and Lewin, {John J.}",

year = "2006",

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AB - The management of patients who have CNS infections is challenging. Therapy for CNS infections is evolving in light of changing microbial resistance patterns and with the introduction of new antimicrobial agents. Knowledge of cerebral inflammation, molecular diagnostics, and the evolving microbial epidemiology are important to optimizing therapy in patients with meningitis. Future investigations into the role of selective immunomodulation and other neuroprotective strategies may lead to significant advances in the management of CNS infection.

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Advances in the Management of Central Nervous System Infections in the ICU

Abstract

ASJC Scopus subject areas

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