Advances in Statistical Approaches to Oncology Drug Development

Anastasia Ivanova; Gary L. Rosner; Olga Marchenko; Tom Parke; Inna Perevozskaya; Yanping Wang

doi:10.1177/2168479013501309

Advances in Statistical Approaches to Oncology Drug Development

Anastasia Ivanova, Gary L. Rosner, Olga Marchenko, Tom Parke, Inna Perevozskaya, Yanping Wang

School of Medicine

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

The authors describe some recent developments in statistical methods and practice in oncology drug development from an academic and an industry perspective. Many adaptive designs were pioneered in oncology, and oncology is still at the forefront of novel methods to enable better and faster go/no-go decision making while controlling the cost.

Original language	English (US)
Pages (from-to)	81-89
Number of pages	9
Journal	Therapeutic Innovation and Regulatory Science
Volume	48
Issue number	1
DOIs	https://doi.org/10.1177/2168479013501309
State	Published - Jan 2014

Keywords

MTD
cancer trial
model-based design
oncology drug development
stopping rule

ASJC Scopus subject areas

Pharmacology, Toxicology and Pharmaceutics (miscellaneous)
Public Health, Environmental and Occupational Health
Pharmacology (medical)

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keywords = "MTD, cancer trial, model-based design, oncology drug development, stopping rule",

author = "Anastasia Ivanova and Rosner, {Gary L.} and Olga Marchenko and Tom Parke and Inna Perevozskaya and Yanping Wang",

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AU - Parke, Tom

AU - Perevozskaya, Inna

AU - Wang, Yanping

PY - 2014/1

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KW - model-based design

KW - oncology drug development

KW - stopping rule

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Advances in Statistical Approaches to Oncology Drug Development

Abstract

Keywords

ASJC Scopus subject areas

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