PROGRES DANS LA CHIMIOTHERAPIE DE LA LEPRE

Translated title of the contribution: Advances in leprosy chemotherapy

J. Grosset

Research output: Contribution to journalArticle

Abstract

The chemotherapy of multibacillary leprosy with dapsone alone has resulted after 15-20 years in the selection and the diffusion of dapsone resistant Mycobacterium leprae. To overcome dapsone resistance, to prevent the selection of organisms resistant to other drugs and to kill the largest proportion of sensitive M. leprae, the chemotherapy of leprosy must rely, as in the chemotherapy of tuberculosis, upon a combination of several drugs. Rifampicin is included in all drug combinations recommended by WHO. The drug combinations have to be given for at least six months in patients with paucibacillary leprosy and two years in patients with multibacillary leprosy.

Original languageFrench
Pages (from-to)17-22
Number of pages6
JournalMedecine Tropicale
Volume44
Issue number1
StatePublished - Jan 1 1984

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ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases

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