Advanced Neonatal NeuroMRI

Research output: Contribution to journalReview articlepeer-review


This article describes the potentials and challenges of quantitative analyses of human neonatal brain images using structural magnetic resonance (MR) imaging and diffusion tensor imaging. To maximize the potential of MR imaging for neonatal brain studies, the combination of both contrasts is highly beneficial. Based on the multicontrast data, a neonate brain atlas was created, which allows automated segmentation of neonate brain MR images. The accuracy, advantages, and potential pitfalls of this atlas-based segmentation approach are discussed. The accurate and reproducible MR imaging quantification achieved by this approach could be an initial step toward the successful clinical evaluation of the neonatal brain.

Original languageEnglish (US)
Pages (from-to)81-91
Number of pages11
JournalMagnetic Resonance Imaging Clinics of North America
Issue number1
StatePublished - Feb 2012


  • Brain atlas
  • Diffusion tensor imaging
  • Neonate
  • Normalization
  • Quantification

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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