Abstract
Patients with osteogenesis imperfecta (OI) may continue to suffer from the sequelae of the disease, such as limb deformities, chronic non-unions, pain and functional impairment, throughout adulthood. In these adult patients, surgical limb reconstruction can be used to address the sequelae of OI and prevent further damage. During limb reconstruction, surgical techniques including multiple osteotomies stabilized by strut allografts, implants and other graft material can be applied safely and effectively, with a relatively low rate of adverse outcomes. Patients undergoing limb reconstruction procedures report an increase in functional capacity and a decrease in discomfort. Complications include migration of implants and non-union of osteotomies, which can usually be addressed successfully through a revision procedure.
Original language | English (US) |
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Title of host publication | Osteogenesis Imperfecta |
Subtitle of host publication | A Translational Approach to Brittle Bone Disease |
Publisher | Elsevier Inc. |
Pages | 453-459 |
Number of pages | 7 |
ISBN (Print) | 9780123971654 |
DOIs | |
State | Published - Sep 2013 |
Keywords
- Adults
- Allografts
- Limb reconstruction
- Osteogenesis imperfecta
- Osteotomies
ASJC Scopus subject areas
- General Dentistry
- General Medicine