Adult granulosa cell tumor associated with endometrial carcinoma: A case report

Cornelius O. Ukah, Okechukwu C. Ikpeze, George U. Eleje, Ahizechukwu C. Eke

Research output: Contribution to journalArticle

Abstract

Introduction. If strict criteria for the diagnosis of carcinoma are used and all patients with granulosa cell tumors are considered, the best estimate of the incidence of associated endometrial carcinomas is under 5%. In patients with granulosa cell tumors, estrogen-dependent endometrial cancers are rarely found, and most of these endometrial cancers are well-differentiated endometrioid adenocarcinomas that carry a good prognosis when detected early. Case presentation. We report the case of a 65-year-old post-menopausal Nigerian woman of the Igbo tribe with an adult granulosa cell tumor that was initially treated as endometrial carcinoma. She underwent a total abdominal hysterectomy and a bilateral salpingo-oophorectomy after histopathologic confirmation of a well-differentiated granulosa cell tumor of the ovary and a nuclear grade 1 adenocarcinoma of the endometrium (International Federation of Obstetricians and Gynecologists stage 1B). She had a good post-operative recovery and was discharged 10 days after treatment. Conclusion: The association between adult granulosa cell tumors of the ovary and endometrial carcinomas is rare. A high index of suspicion as well as good imaging and histopathologic analyses are important in making this diagnosis.

Original languageEnglish (US)
Article number340
JournalJournal of Medical Case Reports
Volume5
DOIs
StatePublished - Aug 4 2011
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)

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