Abstract
Objective: We examined an adult patient who lost one eye due to severe keratomalacia secondary to self-induced vitamin A deficiency. Methods: This case report provides a clinical, ophthalmologic, and laboratory description in addition to a review of the medical literature. Results: A 33-y-old woman with a 17-y history of an eating disorder presented with bilateral conjunctival xerosis, an infected corneal ulcer in the right eye and a large descemetocele in the left eye. Laboratory and clinical findings were consistent with vitamin A deficiency. Despite a tectonic penetrating keratoplasty, her left eye perforated and had to be eviscerated. In parallel, vitamin A replacement improved her clinical status and the ocular findings in her right eye. Conclusions: The present report indicates that vitamin A deficiency secondary to eating disorders should be considered in the differential diagnosis of patients with severe dry eye and corneal ulceration.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 630-633 |
| Number of pages | 4 |
| Journal | Nutrition (Burbank, Los Angeles County, Calif.) |
| Volume | 21 |
| Issue number | 5 |
| DOIs | |
| State | Published - May 2005 |
| Externally published | Yes |
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Keywords
- Blindness
- Eating disorder
- Vitamin A deficiency
- Xerophthalmia
ASJC Scopus subject areas
- Endocrinology, Diabetes and Metabolism
- Surgery
- Medicine (miscellaneous)
Cite this
Adult blindness secondary to vitamin A deficiency associated with an eating disorder. / Velasco Cruz, Antonio Augusto; Attié-Castro, Flávia A.; Fernandes, Sandra L.; Cortes, Jussara Fialho F; Pierre-Filho, Paulo De Tarso P; Rocha, Eduardo Melani; Marchini, Júlio Sérgio.
In: Nutrition (Burbank, Los Angeles County, Calif.), Vol. 21, No. 5, 05.2005, p. 630-633.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Adult blindness secondary to vitamin A deficiency associated with an eating disorder
AU - Velasco Cruz, Antonio Augusto
AU - Attié-Castro, Flávia A.
AU - Fernandes, Sandra L.
AU - Cortes, Jussara Fialho F
AU - Pierre-Filho, Paulo De Tarso P
AU - Rocha, Eduardo Melani
AU - Marchini, Júlio Sérgio
PY - 2005/5
Y1 - 2005/5
N2 - Objective: We examined an adult patient who lost one eye due to severe keratomalacia secondary to self-induced vitamin A deficiency. Methods: This case report provides a clinical, ophthalmologic, and laboratory description in addition to a review of the medical literature. Results: A 33-y-old woman with a 17-y history of an eating disorder presented with bilateral conjunctival xerosis, an infected corneal ulcer in the right eye and a large descemetocele in the left eye. Laboratory and clinical findings were consistent with vitamin A deficiency. Despite a tectonic penetrating keratoplasty, her left eye perforated and had to be eviscerated. In parallel, vitamin A replacement improved her clinical status and the ocular findings in her right eye. Conclusions: The present report indicates that vitamin A deficiency secondary to eating disorders should be considered in the differential diagnosis of patients with severe dry eye and corneal ulceration.
AB - Objective: We examined an adult patient who lost one eye due to severe keratomalacia secondary to self-induced vitamin A deficiency. Methods: This case report provides a clinical, ophthalmologic, and laboratory description in addition to a review of the medical literature. Results: A 33-y-old woman with a 17-y history of an eating disorder presented with bilateral conjunctival xerosis, an infected corneal ulcer in the right eye and a large descemetocele in the left eye. Laboratory and clinical findings were consistent with vitamin A deficiency. Despite a tectonic penetrating keratoplasty, her left eye perforated and had to be eviscerated. In parallel, vitamin A replacement improved her clinical status and the ocular findings in her right eye. Conclusions: The present report indicates that vitamin A deficiency secondary to eating disorders should be considered in the differential diagnosis of patients with severe dry eye and corneal ulceration.
KW - Blindness
KW - Eating disorder
KW - Vitamin A deficiency
KW - Xerophthalmia
UR - http://www.scopus.com/inward/record.url?scp=17844366281&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=17844366281&partnerID=8YFLogxK
U2 - 10.1016/j.nut.2004.12.003
DO - 10.1016/j.nut.2004.12.003
M3 - Article
C2 - 15850971
AN - SCOPUS:17844366281
VL - 21
SP - 630
EP - 633
JO - Nutrition
JF - Nutrition
SN - 0899-9007
IS - 5
ER -