Adrenoleukodystrophy associated with vitiligo and ulcerative colitis

Raja A. Sawaya; Fadi H. Mourad; Samir Najjar; Muhammad Mikati; Gerald V. Raymond

doi:10.1159/000008093

Adrenoleukodystrophy associated with vitiligo and ulcerative colitis

Raja A. Sawaya, Fadi H. Mourad, Samir Najjar, Muhammad Mikati, Gerald V. Raymond

School of Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

Adrenoleukodystrophy (ALD) is an X-linked inherited disorder of lipid metabolism usually presenting in childhood or early adolescence. It is a progressive disease with symptoms of adrenal insufficiency and central nervous system demyelination. The pathology results from the accumulation of very long-chain fatty acids and an inflammatory reaction in the brain white matter. We report a case of ALD associated with adrenal insufficiency and two autoimmune diseases: vitiligo and ulcerative colitis.

Original language	English (US)
Pages (from-to)	169-172
Number of pages	4
Journal	European Neurology
Volume	42
Issue number	3
DOIs	https://doi.org/10.1159/000008093
State	Published - Oct 1999

Keywords

Adrenal insufficiency
Adrenoleukodystrophy
Demyelination
Ulcerative colitis
Very long-chain fatty acids
Vitiligo

ASJC Scopus subject areas

Neurology
Clinical Neurology

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10.1159/000008093

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title = "Adrenoleukodystrophy associated with vitiligo and ulcerative colitis",

abstract = "Adrenoleukodystrophy (ALD) is an X-linked inherited disorder of lipid metabolism usually presenting in childhood or early adolescence. It is a progressive disease with symptoms of adrenal insufficiency and central nervous system demyelination. The pathology results from the accumulation of very long-chain fatty acids and an inflammatory reaction in the brain white matter. We report a case of ALD associated with adrenal insufficiency and two autoimmune diseases: vitiligo and ulcerative colitis.",

keywords = "Adrenal insufficiency, Adrenoleukodystrophy, Demyelination, Ulcerative colitis, Very long-chain fatty acids, Vitiligo",

author = "Sawaya, {Raja A.} and Mourad, {Fadi H.} and Samir Najjar and Muhammad Mikati and Raymond, {Gerald V.}",

year = "1999",

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language = "English (US)",

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AU - Sawaya, Raja A.

AU - Mourad, Fadi H.

AU - Najjar, Samir

AU - Mikati, Muhammad

AU - Raymond, Gerald V.

PY - 1999/10

Y1 - 1999/10

N2 - Adrenoleukodystrophy (ALD) is an X-linked inherited disorder of lipid metabolism usually presenting in childhood or early adolescence. It is a progressive disease with symptoms of adrenal insufficiency and central nervous system demyelination. The pathology results from the accumulation of very long-chain fatty acids and an inflammatory reaction in the brain white matter. We report a case of ALD associated with adrenal insufficiency and two autoimmune diseases: vitiligo and ulcerative colitis.

AB - Adrenoleukodystrophy (ALD) is an X-linked inherited disorder of lipid metabolism usually presenting in childhood or early adolescence. It is a progressive disease with symptoms of adrenal insufficiency and central nervous system demyelination. The pathology results from the accumulation of very long-chain fatty acids and an inflammatory reaction in the brain white matter. We report a case of ALD associated with adrenal insufficiency and two autoimmune diseases: vitiligo and ulcerative colitis.

KW - Adrenal insufficiency

KW - Adrenoleukodystrophy

KW - Demyelination

KW - Ulcerative colitis

KW - Very long-chain fatty acids

KW - Vitiligo

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ER -

Adrenoleukodystrophy associated with vitiligo and ulcerative colitis

Abstract

Keywords

ASJC Scopus subject areas

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