Adrenaline synthesizing neurons in the rostral ventrolateral medulla: a possible role in tonic vasomotor control

Christopher A. Ross, David A. Ruggiero, Tong H. Joh, Dong H. Park, Donald J. Reis

Research output: Contribution to journalArticle


Adrenaline-containing neurons of the rostral ventrolateral medulla (the C1 group) project selectively to autonomic spinal neurons in rats. Stimulation of these neurons electrically or chemically elevates arterial pressure, while neuronal blockade by microinjection of tetrodotoxin bilaterally drops arterial pressure to levels comparable to those produced by spinal cord transection. Adrenaline neurons of the ventral medulla appear necessary for maintaining normal levels of blood pressure, and thus may constitute a tonic vasomotor center.

Original languageEnglish (US)
Pages (from-to)356-361
Number of pages6
JournalBrain research
Issue number2
StatePublished - Aug 29 1983
Externally publishedYes



  • adrenaline neurons
  • tonic vasomotor control
  • ventrolateral medulla

ASJC Scopus subject areas

  • Neuroscience(all)
  • Molecular Biology
  • Clinical Neurology
  • Developmental Biology

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