Adrenal function during the use of dexamethasone aerosols in the treatment of ragweed hay fever

Philip S. Norman, Walter L. Winkenwerder, Benigno F. Agbayani, Claude J. Migeon

Research output: Contribution to journalArticle

Abstract

The use of Freon propelled dexamethasone nasal spray (Turbinaire) in nasal allergy successfully alleviates symptoms but may cause partial suppression of adrenal function. To evaluate the significance of adrenal suppression in hay fever, the 17-hydroxy-steroid excretion of seven patients was followed through a ragweed hay fever season. Partial adrenal suppression was observed in four of the patients and temporary complete suppression was observed in one. After discontinuance of the drug a prompt return of normal adrenal secretion was observed. The risk of long-term adrenal suppression from the seasonal use of Turbinaire seems small.

Original languageEnglish (US)
Pages (from-to)57-61
Number of pages5
JournalJournal of Allergy
Volume40
Issue number1
StatePublished - Jul 1967

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Ambrosia
Seasonal Allergic Rhinitis
Aerosols
Dexamethasone
Chlorofluorocarbons
Nasal Sprays
Nose
Hypersensitivity
Steroids
Therapeutics
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Adrenal function during the use of dexamethasone aerosols in the treatment of ragweed hay fever. / Norman, Philip S.; Winkenwerder, Walter L.; Agbayani, Benigno F.; Migeon, Claude J.

In: Journal of Allergy, Vol. 40, No. 1, 07.1967, p. 57-61.

Research output: Contribution to journalArticle

Norman, PS, Winkenwerder, WL, Agbayani, BF & Migeon, CJ 1967, 'Adrenal function during the use of dexamethasone aerosols in the treatment of ragweed hay fever', Journal of Allergy, vol. 40, no. 1, pp. 57-61.
Norman, Philip S. ; Winkenwerder, Walter L. ; Agbayani, Benigno F. ; Migeon, Claude J. / Adrenal function during the use of dexamethasone aerosols in the treatment of ragweed hay fever. In: Journal of Allergy. 1967 ; Vol. 40, No. 1. pp. 57-61.
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