ADPr-ChAP: Mapping ADP-Ribosylation onto the Genome

Robert Lyle McPherson, Anthony K.L. Leung

Research output: Contribution to journalShort survey

Abstract

In this issue of Molecular Cell, Bartolomei et al. (2016) describe a chromatin affinity precipitation method using well-characterized ADP-ribose binding domains to provide the first genome-wide view of ADP-ribosylated chromatin. Here, we discuss its potential applications and the remaining challenges ahead.

Original languageEnglish (US)
Pages (from-to)327-328
Number of pages2
JournalMolecular cell
Volume61
Issue number3
DOIs
StatePublished - Feb 4 2016

ASJC Scopus subject areas

  • Molecular Biology
  • Cell Biology

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