Adolescents and Young Adults With Down Syndrome Presenting to a Medical Clinic With Depression: Phenomenology and Characterization Using the Reiss Scales and Aberrant Behavior Checklist

George T. Capone, Jenna M. Aidikoff, Parag Goyal

Research output: Contribution to journalArticlepeer-review

Abstract

Caretakers of adolescents and young adults with Down syndrome (DS) may report the onset of a depressive illness in previously mentally well individuals. However, the behavioral phenomenology of these conditions has not been well characterized. We ascertained a cohort of DS patient-subjects presenting to a specialty clinic with medical and/or mental health concerns between 2002 and 2009.Caretakers completed questionnaires measuring psychopathology and maladaptive behavior on all subjects. When psychopathology was present a psychiatric diagnosis was made using Diagnostic and Statistical Manual of Mental Disorders, 4th Edition-Revised (American Psychiatric Association, 1994) criteria. DS subjects without mental health concerns served as a control group. Cases scored significantly higher (p <.0001) on the Anxiety, Attention, Autism, Depression, Psychosis, Withdrawn, Other behavior, and Total score of the Reiss Scales for Children's Dual Diagnosis (RSCDD) and the Stereotypy and Lethargy subscales of the Aberrant Behavior Checklist compared with Control subjects. Cases with major depressive illness also scored significantly higher (p &.01) on the Anxiety, Depression, Somatoform, Other behavior, and Total scores of the RSCDD compared to cases without depression. The RSCDD appears useful for capturing caretaker-reported psychopathology in clinically referred subjects with DS and major depressive illness.

Original languageEnglish (US)
Pages (from-to)244-264
Number of pages21
JournalJournal of Mental Health Research in Intellectual Disabilities
Volume4
Issue number4
DOIs
StatePublished - Oct 1 2011

Keywords

  • Aberrant Behavior Checklist
  • Down syndrome
  • Reiss Scales for Children's Dual Diagnosis
  • depression
  • psychosis

ASJC Scopus subject areas

  • Psychiatry and Mental health

Fingerprint Dive into the research topics of 'Adolescents and Young Adults With Down Syndrome Presenting to a Medical Clinic With Depression: Phenomenology and Characterization Using the Reiss Scales and Aberrant Behavior Checklist'. Together they form a unique fingerprint.

Cite this